Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | TACR2 | P21452 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SHBG | P04278 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1243639 | 1.00 | PTGS2 (0.40) | PTGS2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL4624237 | 1.00 | PTGS2 (0.40) | PTGS2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL2883267 | 1.00 | PTGS2 (0.40) | PTGS2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL4623440 | 1.00 | PTGS2 (0.40) | PTGS2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL8390626 | 0.89 | PTGS2 (0.34) | PTGS2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL3423379 | 0.81 | PTGS2 (0.34) | PTGS2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL1717330 | 0.81 | PTGS2 (0.34) | PTGS2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL1717457 | 0.81 | PTGS2 (0.34) | PTGS2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL7570539 | 0.81 | PTGS2 (0.34) | PTGS2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL11787936 | 0.81 | PTGS2 (0.34) | PTGS2ESR1ADRA2AADORA3TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2766046-B1 | METAL-ORGANIC FRAMEWORKS WITH EXCEPTIONALLY LARGE PORE APERATURES | UNIV CALIFORNIA (US) | 2017-08-02 | — | — | EP | disclosed |
| US-9669098-B2 | Metal-organic frameworks with exceptionally large pore aperatures | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-06-06 | — | — | US | disclosed |
| US-20160008472-A1 | METAL-ORGANIC FRAMEWORKS WITH EXCEPTIONALLY LARGE PORE APERATURES | UNITED STATES DEPARTMENT OF ENERGY | 2016-01-14 | — | — | US | disclosed |
| US-9078922-B2 | Metal-organic frameworks with exceptionally large pore aperatures | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-07-14 | — | — | US | disclosed |
| US-20130096210-A1 | METAL-ORGANIC FRAMEWORKS WITH EXCEPTIONALLY LARGE PORE APERATURES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-04-18 | — | — | US | disclosed |
| US-8207337-B2 | Reagent for organic synthesis reaction containing organic triol borate salt | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2012-06-26 | — | — | US | disclosed |
| US-20100087646-A1 | REAGENT FOR ORGANIC SYNTHESIS REACTION CONTAINING ORGANIC TRIOL BORATE SALT | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1337520-B1 | SUBSTITUTED 5-ARYL AND 5-HETEROARYL-2-(2-HYDROXYPHENYL)-2H-BENZOTRIAZOLE DERIVATIVES AS UV ABSORBERS | CIBA SC HOLDING AG (CH) | 2004-12-15 | — | — | EP | disclosed |
| EP-1337520-A1 | SUBSTITUTED 5-ARYL AND 5-HETEROARYL-2-(2-HYDROXYPHENYL)-2H-BENZOTRIAZOLE DERIVATIVES AS UV ABSORBERS | Ciba SC Holding AG (CH) | 2003-08-27 | — | — | EP | disclosed |
| WO-2002042281-A1 | SUBSTITUTED 5-ARYL AND 5-HETEROARYL-2-(2-HYDROXYPHENYL)-2H-BENZOTRIAZOLE DERIVATIVES AS UV ABSORBERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-05-30 | — | — | WO | disclosed |
| EP-0579604-A1 | CONDUCTIVE POLYMERS WITH CONJUGATED DOUBLE BONDS. | WAKKER CHEMIE GMBH (DE) | 1994-01-26 | — | — | EP | disclosed |
| WO-1992018552-A1 | CONDUCTIVE POLYMERS WITH CONJUGATED DOUBLE BONDS | WACKER-CHEMIE GMBH (DE) | 1992-10-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087646-A1 | REAGENT FOR ORGANIC SYNTHESIS REACTION CONTAINING ORGANIC TRIOL BORATE SALT | ORC3, OXSR1, OSTC | PTGS2 4673/4885ESR1 1651/4885ADRA2A 4327/4885 |
| US-20160008472-A1 | METAL-ORGANIC FRAMEWORKS WITH EXCEPTIONALLY LARGE PORE APERATURES | AP3M1, AP2M1, AP2A2 | PTGS2 2129/4885ESR1 3788/4885ADRA2A 4332/4885 |
| US-20130096210-A1 | METAL-ORGANIC FRAMEWORKS WITH EXCEPTIONALLY LARGE PORE APERATURES | AP3M1, AP2M1, AP2A2 | PTGS2 2129/4885ESR1 3788/4885ADRA2A 4332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.