Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 20/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 11/20 | 0.52 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL325892 | 0.85 | S1PR5 (0.68) | S1PR5S1PR1S1PR3 | |
| SCHEMBL15137135 | 0.84 | S1PR5 (0.54) | S1PR5S1PR1S1PR3 | |
| SCHEMBL10266087 | 0.81 | S1PR5 (0.51) | S1PR5S1PR1S1PR3 | |
| SCHEMBL325671 | 0.77 | S1PR5 (0.58) | S1PR5S1PR1S1PR3 | |
| SCHEMBL29797988 | 0.77 | S1PR5 (0.58) | S1PR5S1PR1S1PR3 | |
| Trifluoroacetic Acid SCHEMBL326924 | 0.76 | S1PR5 (0.54) | S1PR5S1PR1S1PR3 | |
| SCHEMBL326261 | 0.76 | S1PR5 (0.60) | S1PR5S1PR1S1PR3 | |
| SCHEMBL326726 | 0.75 | S1PR5 (0.74) | S1PR5S1PR1S1PR3 | |
| SCHEMBL327488 | 0.72 | S1PR5 (0.50) | S1PR5S1PR1S1PR3 | |
| SCHEMBL10265152 | 0.72 | S1PR5 (0.56) | S1PR5S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590955-A1 | SPIRO-CYCLIC AMINE DERIVATIVES AS S1P MODULATORS | ABBVIE B.V. (NL) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012004378-A1 | SPIRO-CYCLIC AMINE DERIVATIVES AS S1P MODULATORS | ABBOTT HEALTHCARE PRODUCTS B.V. (NL) | 2012-01-12 | — | — | WO | disclosed |