⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1299627 | 1.00 | — | — | |
| SCHEMBL2089060 | 1.00 | — | — | |
| Iodide SCHEMBL38651116 | 0.98 | — | — | |
| SCHEMBL12018255 | 0.93 | — | — | |
| SCHEMBL88583 | 0.93 | — | — | |
| SCHEMBL14087966 | 0.93 | — | — | |
| SCHEMBL18967338 | 0.91 | CHRM1 (0.45) | — | |
| SCHEMBL31029450 | 0.84 | — | — | |
| SCHEMBL2089866 | 0.84 | — | — | |
| SCHEMBL30315163 | 0.78 | CHRM1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1367 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114920682-A | Method for reducing proline into prolinol and preparation method of 1-methylpyrrolidine-2-acrylic acid | 重庆医药高等专科学校 | 2022-08-19 | — | — | CN | claimed |
| CN-114736146-A | Preparation method of novel 1-methylpyrrolidine-2-acrylic acid | 重庆医药高等专科学校 | 2022-07-12 | — | — | CN | claimed |
| US-20220194931-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | INCYTE CORPORATION | 2022-06-23 | — | — | US | claimed |
| CN-109912489-B | Method for synthesizing 2, 3-dihydrotryptamine compound by alkylation of non-activated olefin | 哈尔滨商业大学 | 2022-05-13 | — | — | CN | claimed |
| CN-114409584-A | Preparation method of 1-methylpyrrolidine-2-formaldehyde | 重庆医药高等专科学校 | 2022-04-29 | — | — | CN | claimed |
| CN-111018767-B | Preparation method of D-proline derivative and intermediate thereof | 江苏美迪克化学品有限公司 | 2021-09-28 | — | — | CN | claimed |
| CN-111018767-A | Preparation method of D-proline derivative and intermediate thereof | 江苏美迪克化学品有限公司 | 2020-04-17 | — | — | CN | claimed |
| CN-110582493-A | Benzoxazole derivatives as immunomodulators | 因赛特公司 | 2019-12-17 | — | — | CN | claimed |
| EP-3558985-A1 | BENZOOXAZOLE DERIVATIVES AS IMMUNOMODULATORS | Incyte Corporation (US) | 2019-10-30 | — | — | EP | claimed |
| CN-108314639-B | Compound (E) -3-(1- methylpyrrolidin- 2- yl)-acrylic acid hydrochloride and synthetic method | 山东铂源药业有限公司 | 2019-04-30 | — | — | CN | claimed |
| CN-1292379-A | Preparation method of pyrazolzo [4,3-d] pyrimidine-7-ketone-3-pyridyl sulfonyl compound and its intermediate | PFIZER (US) | 2001-04-25 | — | — | CN | claimed |
| CN-1061656-C | Process for the preparation of a tetrazole derivative in two crystalline forms and novel crystalline form of said derivative | SANOFI SA (FR) | 2001-02-07 | — | — | CN | claimed |
| CN-1281433-A | Hydroxamic acid derivatives as matrix metalloproteinase (MMP) inhibitors | PFIZER LTD (US) | 2001-01-24 | — | — | CN | claimed |
| CN-1058708-C | Quinolone derivative for treatment of urinary incontinence | ZENECA LTD (GB) | 2000-11-22 | — | — | CN | claimed |
| CN-1255497-A | Process for preparing pyrazolo [4, 3-d ] pyrimidin-7-ones and intermediates thereof | PFIZER RES & DEV (IE) | 2000-06-07 | — | — | CN | claimed |
| CN-1196097-A | Electrolytic plate stack cell | BASF AG (DE) | 1998-10-14 | — | — | CN | claimed |
| CN-1187126-A | Pharmaceutical formulations of highly lipophilic camptothecin devivatives | BIONUMERIK PHARMACEUTICALS INC (US) | 1998-07-08 | — | — | CN | claimed |
| CN-1168376-A | Process for preparing sildenafil | PFIZER RES & DEV (IE) | 1997-12-24 | — | — | CN | claimed |
| CN-1146202-A | Quinolone derivative for treatment of urinary incontinence | ZENECA LTD (GB) | 1997-03-26 | — | — | CN | claimed |
| CN-86106546-A | The preparation method of Pyridione derivatives | — | 1987-05-20 | — | — | CN | claimed |