⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14087966 | 1.00 | — | — | |
| SCHEMBL12018255 | 1.00 | — | — | |
| SCHEMBL18967338 | 0.98 | CHRM1 (0.45) | — | |
| SCHEMBL327784 | 0.93 | — | — | |
| SCHEMBL2089060 | 0.93 | — | — | |
| SCHEMBL1299627 | 0.93 | — | — | |
| Iodide SCHEMBL38651116 | 0.91 | — | — | |
| SCHEMBL28301668 | 0.85 | CHRM1 (0.45) | — | |
| SCHEMBL31029450 | 0.82 | — | — | |
| SCHEMBL2089866 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107556309-B | Pharmaceutical application of polysubstituted tetrahydronaphthyridine compound and preparation method thereof | 浙江永宁药业股份有限公司 | 2020-12-01 | — | — | CN | claimed |
| JP-4508413-B2 | — | — | 2010-07-21 | — | — | JP | claimed |
| CN-101778568-A | aqueous microemulsions containing organic insecticide compounds | BASF SE | 2010-07-14 | — | — | CN | claimed |
| US-20060270606-A1 | Dolastatin 15 derivatives | ABBOTT GMBH & CO., KG (DE) | 2006-11-30 | — | — | US | claimed |
| CN-1268636-C | Dolastatin 15 derivatives | ABSF AG (DE) | 2006-08-09 | — | — | CN | claimed |
| EP-0991658-B1 | DOLASTATIN 15 DERIVATIVES | ABBOTT GMBH & CO KG (DE) | 2005-12-28 | — | — | EP | claimed |
| US-20030153505-A1 | Dolastatin 15 derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2003-08-14 | — | — | US | claimed |
| US-6143721-A | FOR TREATING CANCER IN MAMMALS | BASF AKTIENGESELLSCHAFT (DE) | 2000-11-07 | — | — | US | claimed |
| EP-0991658-A1 | DOLASTATIN 15 DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2000-04-12 | — | — | EP | claimed |
| WO-1999003879-A1 | DOLASTATIN 15 DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1999-01-28 | — | — | WO | claimed |
| WO-2023142600-A1 | AMINO LIPID, PREPARATION METHOD THEREFOR, AND USE THEREOF | 深圳虹信生物科技有限公司 | 2023-08-03 | — | — | WO | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-20210277175-A1 | AMINE FOR LOW-EMISSION EPOXY RESIN COMPOSITIONS | SIKA TECHNOLOGY AG (CH) | 2021-09-09 | — | — | US | disclosed |
| US-11046809-B2 | Amine for low-emission epoxy resin compositions | SIKA TECHNOLOGY AG (CH) | 2021-06-29 | — | — | US | disclosed |
| CN-107556309-B | Pharmaceutical application of polysubstituted tetrahydronaphthyridine compound and preparation method thereof | 浙江永宁药业股份有限公司 | 2020-12-01 | — | — | CN | disclosed |
| US-20030153505-A1 | Dolastatin 15 derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2003-08-14 | — | — | US | disclosed |
| US-6458765-B1 | POLYPEPTIDES AS ANTICANCER AGENTS AND AGAINST CELL PROLIFERATION | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-01 | — | — | US | disclosed |
| US-6143721-A | FOR TREATING CANCER IN MAMMALS | BASF AKTIENGESELLSCHAFT (DE) | 2000-11-07 | — | — | US | disclosed |
| EP-0991658-A1 | DOLASTATIN 15 DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999003879-A1 | DOLASTATIN 15 DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1999-01-28 | — | — | WO | disclosed |