SCHEMBL3278317

SCHEMBL3278317

c1ccc(Cc2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.58
HPGD P15428 3/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
MAPK14 Q16539 4/20 0.52
MAPK13 O15264 3/20 0.52
MAPK12 P53778 3/20 0.52
MAPK11 Q15759 3/20 0.52
GCGR P47871 2/20 0.52
GAA P10253 2/20 0.50
ALDH1A1 P00352 2/20 0.49
LMNA P02545 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
NR1H2 P55055 1/20 0.49
NR1H3 Q13133 1/20 0.49
RAF1 P04049 1/20 0.47
MAPK9 P45984 1/20 0.47
PKM P14618 1/20 0.46
TSHR P16473 1/20 0.46
KMT2A Q03164 1/20 0.46
GSK3A P49840 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28404728 0.90 MAPK14 (0.58) KDM4EHPGDSMN1; SMN2MAPK14MAPK13
SCHEMBL26110690 0.89 MAPK13 (0.52) KDM4EHPGDSMN1; SMN2MAPK14MAPK13
SCHEMBL28400735 0.86 MAPK13 (0.51) KDM4EHPGDSMN1; SMN2MAPK14MAPK13
SCHEMBL31305525 0.85 MAPK13 (0.50) KDM4EHPGDSMN1; SMN2MAPK14MAPK13
SCHEMBL27828715 0.85 MAPT (0.56) KDM4EHPGDSMN1; SMN2MAPK14MAPK13
SCHEMBL26113574 0.85 MAPK13 (0.50) KDM4EHPGDSMN1; SMN2MAPK14MAPK13
SCHEMBL28403324 0.84 KDM4E (0.49) KDM4EHPGDSMN1; SMN2MAPK14MAPK13
SCHEMBL14060682 0.83 KDM4E (0.47) KDM4EHPGDSMN1; SMN2MAPK14MAPK13
SCHEMBL4427792 0.83 ALOX5 (0.55) MAPK14MAPK13MAPK12MAPK11GCGR
SCHEMBL11835462 0.82 GAA (0.50) KDM4EHPGDSMN1; SMN2GAAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250215572-A1 SURFACE TREATMENT AGENT FOR COPPER OR COPPER ALLOY SHIKOKU CHEMICALS CORPORATION (JP) 2025-07-03 US disclosed
EP-4506488-A1 SURFACE TREATMENT AGENT FOR COPPER OR COPPER ALLOY Shikoku Chemicals Corporation (JP) 2025-02-12 EP disclosed
CN-118922584-A Surface treating agent for copper or copper alloy 四国化成工业株式会社 2024-11-08 CN disclosed
WO-2023190263-A1 SURFACE TREATMENT AGENT FOR COPPER OR COPPER ALLOY 四国化成工業株式会社 2023-10-05 WO disclosed
US-RE41254-E1 Synthesis procedure for biphenylimidazolyl-(1)-phenylmethane and related compounds MANUFACTURAS HUMBERTO TO BUELE HIJOS, S. (SV) 2010-04-20 US disclosed
JP-2010070535-A 2-BENZYL-4,5-DIPHENYLIMIDAZOLE COMPOUND SHIKOKU CHEM CORP 2010-04-02 JP disclosed
CN-101443036-A Reagents and methods for cancer treatment and prevention BUCK INST FOR AGE RES (US) 2009-05-27 CN disclosed
US-7112681-B2 Synthesis procedure for imidazolyl carbinol derivatives such as biphenylimidazolyl-(1)-phenylmethane MANUFACTURAS HUMBERTO BUKELE E HIJOS, S.A DE C.V (SV) 2006-09-26 US disclosed
US-6870057-B1 Reducing 4-phenylbenzophenone to alcohols, then condensing the intermediates with imidazole, to form bifonazole used as fungicides MANUFACTURAS HUMBERTO BUKELE E HIJOS, S.A. DE C.V. (SV) 2005-03-22 US disclosed
US-20040267027-A1 Synthesis procedure for biphenylimidazolyl-(1)-phenylmethane and related compounds MANUFACTURAS HUMBERTO TO BUELE HIJOS, S. 2004-12-30 US disclosed
US-5663053-A COENZYME A TRANSACYLASE FOR SCREENING SMITHKLINE BEECHAM CORPORATION (US) 1997-09-02 US disclosed
US-5648373-A CoA-IT and PAF inhibitors SMITHKLINE BEECHAM CORPORATION (US) 1997-07-15 US disclosed
EP-0626969-A4 CoA-IT AND PAF INHIBITORS. SMITHKLINE BEECHAM CORP (US) 1995-04-19 EP disclosed
EP-0626969-A1 CoA-IT AND PAF INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 1994-12-07 EP disclosed
WO-1993016674-A1 CoA-IT AND PAF INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 1993-09-02 WO disclosed
EP-0550502-A1 SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1993-07-14 EP disclosed
WO-1992016681-A2 BINDER COATED DISCONTINUOUS FIBERS WITH ADHERED PARTICULATE MATERIALS WEYERHAEUSER CO (US) 1992-10-01 WO disclosed
WO-1992004330-A1 SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1992-03-19 WO disclosed
EP-0094329-A1 Tanning process for rendering leathers mycostatic, antimycosic and antifungicidal, and articles produced thereby Roux, Joel (FR) 1983-11-16 EP disclosed
US-4118487-A ANTIMICROBIAL AGENTS BAYER AKTIENGESELLSCHAFT (DE) 1978-10-03 US disclosed