Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2162875 | 0.96 | THRB (0.38) | THRBGSTP1HDAC4HDAC2HDAC8 | |
| SCHEMBL9837309 | 0.95 | THRB (0.37) | THRBGSTP1HDAC4HDAC2HDAC8 | |
| SCHEMBL9837314 | 0.95 | THRB (0.37) | THRBGSTP1HDAC4HDAC2HDAC8 | |
| SCHEMBL9837099 | 0.95 | THRB (0.37) | THRBGSTP1HDAC4HDAC2HDAC8 | |
| SCHEMBL29404200 | 0.91 | THRB (0.35) | THRBGSTP1HDAC4HDAC2HDAC8 | |
| SCHEMBL1399627 | 0.91 | THRB (0.35) | THRBGSTP1HDAC4HDAC2HDAC8 | |
| Ether SCHEMBL22613517 | 0.89 | THRB (0.41) | THRBGSTP1CTSKTHRA | |
| SCHEMBL22092284 | 0.82 | HDAC4 (0.37) | GSTP1HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL31192620 | 0.82 | THRB (0.40) | THRBGSTP1THRA | |
| SCHEMBL2499163 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6150479-A | CURABLE ADHESIVES FOR HEAT RESISTANCE | LOCTITE CORPORATION (US) | 2000-11-21 | — | — | US | claimed |
| WO-2000031149-A1 | RADICAL-CURABLE ADHESIVE COMPOSITIONS, REACTION PRODUCTS OF WHICH DEMONSTRATE SUPERIOR RESISTANCE TO THERMAL DEGRADATION | LOCTITE CORPORATION (US) | 2000-06-02 | — | — | WO | claimed |
| US-10100226-B2 | Thermally resistant anaerobically curable compositions | Henkel IP & Holding GmbH (DE) | 2018-10-16 | — | — | US | disclosed |
| CN-106047183-B | Anaerobic curing composition | 汉高知识产权控股有限责任公司 | 2018-03-02 | — | — | CN | disclosed |
| US-9580530-B2 | Anaerobically curable compositions | Henkel IP & Holding GmbH (DE) | 2017-02-28 | — | — | US | disclosed |
| US-20160319162-A1 | THERMALLY RESISTANT ANAEROBICALLY CURABLE COMPOSITIONS | HENKEL AG & CO. KGAA (DE) | 2016-11-03 | — | — | US | disclosed |
| CN-106047183-A | ANAEROBICALLY CURABLE COMPOSITIONS | 汉高知识产权控股有限责任公司 | 2016-10-26 | — | — | CN | disclosed |
| US-8835533-B2 | Thermally resistant anaerobically curable compositions | Henkel US IP LLC (US) | 2014-09-16 | — | — | US | disclosed |
| EP-2207850-B1 | THERMALLY RESISTANT ANAEROBICALLY CURABLE COMPOSITIONS | HENKEL CORP (US) | 2013-06-05 | — | — | EP | disclosed |
| US-20120231286-A1 | ANAEROBICALLY CURABLE COMPOSITIONS | LOCTITE (R&D) LIMITED (IE) | 2012-09-13 | — | — | US | disclosed |
| CN-102549059-A | Anaerobic curing composition | HENKEL CORP | 2012-07-04 | — | — | CN | disclosed |
| EP-2207850-A2 | THERMALLY RESISTANT ANAEROBICALLY CURABLE COMPOSITIONS | Henkel Corporation (US) | 2010-07-21 | — | — | EP | disclosed |
| US-20100086796-A1 | THERMALLY RESISTANT ANAEROBICALLY CURABLE COMPOSITIONS | HENKEL CORPORATION (US) | 2010-04-08 | — | — | US | disclosed |
| WO-2009058250-A2 | THERMALLY RESISTANT ANAEROBICALLY CURABLE COMPOSITIONS | HENKEL CORPORATION (US) | 2009-05-07 | — | — | WO | disclosed |
| US-20090022894-A1 | Thermally Resistant Anaerobically Curable Compositions | HENKEL CORPORATION (US) | 2009-01-22 | — | — | US | disclosed |
| WO-2009011819-A2 | THERMALLY RESISTANT ANAEROBICALLY CURABLE COMPOSITIONS | HENKEL CORPORATION (US) | 2009-01-22 | — | — | WO | disclosed |
| US-6150479-A | CURABLE ADHESIVES FOR HEAT RESISTANCE | LOCTITE CORPORATION (US) | 2000-11-21 | — | — | US | disclosed |
| WO-2000031149-A1 | RADICAL-CURABLE ADHESIVE COMPOSITIONS, REACTION PRODUCTS OF WHICH DEMONSTRATE SUPERIOR RESISTANCE TO THERMAL DEGRADATION | LOCTITE CORPORATION (US) | 2000-06-02 | — | — | WO | disclosed |