Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 5/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | PTAFR | P25105 | 1/20 | 0.31 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.31 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3279424 | 1.00 | VDR (0.46) | VDRBACE1MTNR1AMTNR1BPTAFR | |
| SCHEMBL3279418 | 1.00 | VDR (0.46) | VDRBACE1MTNR1AMTNR1BPTAFR | |
| SCHEMBL6884293 | 0.89 | BACE1 (0.35) | VDRBACE1CYP26A1CYP26B1 | |
| SCHEMBL6884295 | 0.89 | BACE1 (0.35) | VDRBACE1CYP26A1CYP26B1 | |
| SCHEMBL6155830 | 0.89 | BACE1 (0.35) | VDRBACE1CYP26A1CYP26B1 | |
| SCHEMBL3280115 | 0.89 | VDR (0.41) | VDRBACE1 | |
| SCHEMBL3278871 | 0.88 | VDR (0.46) | VDRBACE1 | |
| SCHEMBL3278878 | 0.88 | VDR (0.46) | VDRBACE1 | |
| SCHEMBL3278876 | 0.88 | VDR (0.46) | VDRBACE1 | |
| SCHEMBL3280019 | 0.85 | VDR (0.45) | VDRBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700657-B2 | Vitamin D analogs | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-04-20 | — | — | US | disclosed |