Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 12/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 4/20 | 0.36 |
| ▸ | F2 | P00734 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3280003 | 0.87 | VDR (0.41) | VDR | |
| SCHEMBL3279995 | 0.87 | VDR (0.41) | VDR | |
| SCHEMBL3280000 | 0.87 | VDR (0.41) | VDR | |
| SCHEMBL3285825 | 0.87 | VDR (0.49) | VDRMAOBNR4A2NR4A1NR4A3 | |
| SCHEMBL3280269 | 0.87 | VDR (0.49) | VDRMAOBNR4A2NR4A1NR4A3 | |
| SCHEMBL3285828 | 0.87 | VDR (0.49) | VDRMAOBNR4A2NR4A1NR4A3 | |
| SCHEMBL3280564 | 0.81 | VDR (0.47) | VDRMAOBNR4A2NR4A1NR4A3 | |
| SCHEMBL3280570 | 0.81 | VDR (0.47) | VDRMAOBNR4A2NR4A1NR4A3 | |
| SCHEMBL3280573 | 0.81 | VDR (0.47) | VDRMAOBNR4A2NR4A1NR4A3 | |
| SCHEMBL3279961 | 0.81 | VDR (0.73) | VDRMAOBNR4A2NR4A1NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700657-B2 | Vitamin D analogs | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-04-20 | — | — | US | disclosed |
| EP-1395538-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2009-12-30 | — | — | EP | disclosed |
| US-20040224929-A1 | Novel vitamin D analogs | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-11-11 | — | — | US | disclosed |