Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | BDKRB1 | P46663 | 13/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | PREP | P48147 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3281648 | 0.89 | SMN1; SMN2 (0.50) | SMN1; SMN2BDKRB1KCNH2ALDH1A1CYP1A2 | |
| SCHEMBL15103872 | 0.88 | SMN1; SMN2 (0.54) | SMN1; SMN2BDKRB1KCNH2ALDH1A1CYP1A2 | |
| SCHEMBL3281262 | 0.88 | BDKRB1 (0.50) | SMN1; SMN2BDKRB1KCNH2ALDH1A1CYP1A2 | |
| SCHEMBL3274343 | 0.88 | SMN1; SMN2 (0.48) | SMN1; SMN2BDKRB1KCNH2USP30 | |
| Hydrochloric Acid SCHEMBL3277445 | 0.88 | SMN1; SMN2 (0.51) | SMN1; SMN2BDKRB1KCNH2ALDH1A1CYP1A2 | |
| SCHEMBL15103982 | 0.87 | BDKRB1 (0.55) | BDKRB1KCNH2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL3275296 | 0.87 | SMN1; SMN2 (0.66) | SMN1; SMN2BDKRB1KCNH2ALDH1A1CYP1A2 | |
| SCHEMBL3275545 | 0.86 | BDKRB1 (0.57) | BDKRB1KCNH2ALDH1A1HPGD | |
| SCHEMBL3278506 | 0.86 | BDKRB1 (0.57) | BDKRB1KCNH2ALDH1A1HPGD | |
| SCHEMBL3274439 | 0.86 | NPC1 (0.47) | SMN1; SMN2BDKRB1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2076491-B1 | NEW BENZAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | RICHTER GEDEON NYRT (HU) | 2013-07-17 | — | — | EP | claimed |
| US-8481527-B2 | Benzamide derivatives as bradykinin antagonists | RICHTER GEDEON NYRT. (HU) | 2013-07-09 | — | — | US | claimed |
| US-20100087423-A1 | NEW BENZAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | RICHTER GEDEON NYRT. (HU) | 2010-04-08 | — | — | US | claimed |
| EP-2076491-B1 | NEW BENZAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | RICHTER GEDEON NYRT (HU) | 2013-07-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087423-A1 | NEW BENZAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | BDKRB1, BDKRB2, HRH1 | SMN1; SMN2 4508/4885BDKRB1 1/4885KCNH2 55/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.