Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC2 | Q92887 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3282001 | 0.91 | ABCC2 (0.44) | ABCC2 | |
| SCHEMBL3281310 | 0.84 | ABCC2 (0.57) | ABCC2 | |
| SCHEMBL3280877 | 0.83 | ABCC2 (0.54) | ABCC2 | |
| SCHEMBL3285147 | 0.83 | ABCC2 (0.49) | ABCC2 | |
| SCHEMBL3285025 | 0.82 | ABCC2 (0.58) | ABCC2 | |
| SCHEMBL3281497 | 0.81 | ABCC2 (0.52) | ABCC2 | |
| SCHEMBL3289159 | 0.80 | ABCC2 (0.53) | ABCC2 | |
| SCHEMBL3281948 | 0.80 | ABCC2 (0.51) | ABCC2 | |
| SCHEMBL3280848 | 0.80 | ABCC2 (0.55) | ABCC2 | |
| SCHEMBL3288453 | 0.80 | ABCC2 (0.52) | ABCC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709503-B2 | Pyrrol derivatives with antibacterial activity | ASTRAZENECA AB (SE) | 2010-05-04 | — | — | US | disclosed |
| EP-1664025-B1 | PYRROL DERIVATIVES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2007-09-19 | — | — | EP | disclosed |
| EP-1664025-A1 | PYRROL DERIVATIVES WITH ANTIBACTERIAL ACTIVITY | AstraZeneca AB (SE) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005026149-A1 | PYRROL DERIVATIVES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2005-03-24 | — | — | WO | disclosed |