Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.46 |
| ▸ | GPR183 | P32249 | 1/20 | 0.46 |
| ▸ | GHSR | Q92847 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | FASN | P49327 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1025449 | 0.89 | HDAC6 (0.53) | MAPK14KDM4EPRMT5WDR77GPR183 | |
| SCHEMBL2279415 | 0.84 | HDAC6 (0.55) | MAPK14PRMT5WDR77GPR183 | |
| SCHEMBL3281279 | 0.81 | MYC (0.58) | MYCKDM4EALDH1A1HPGD | |
| SCHEMBL1081769 | 0.79 | CHRM2 (0.42) | PRMT5WDR77HSD11B1 | |
| SCHEMBL4150881 | 0.77 | MAPK14 (0.60) | MAPK14PRMT5WDR77GPR183GHSR | |
| SCHEMBL105928 | 0.76 | KDM4E (0.72) | MAPK14KDM4EALDH1A1HPGDENPP2 | |
| SCHEMBL8534513 | 0.76 | MAPK14 (0.64) | MAPK14ALDH1A1HPGDGPR183GHSR | |
| SCHEMBL22216445 | 0.76 | MAPK14 (0.64) | MAPK14GPR183GHSRHSD11B1MGLL | |
| SCHEMBL30226931 | 0.76 | MAPK14 (0.64) | MAPK14ALDH1A1HPGDGPR183GHSR | |
| SCHEMBL30329646 | 0.76 | MAPK14 (0.64) | MAPK14GPR183GHSRHSD11B1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705017-B2 | Compounds for treatment of neurodegenerative diseases | EN VIVO PHARMACEUTICALS, INC. (US) | 2010-04-27 | — | — | US | disclosed |
| US-20060004041-A1 | Compounds for treatment of neurodegenerative diseases | ENVIVO PHARMACEUTICALS, INC. | 2006-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004041-A1 | Compounds for treatment of neurodegenerative diseases | HDAC5, HDAC6, HDAC3 | MYC 4493/4885MAPK14 3358/4885KDM4E 171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.