SCHEMBL3282010

SCHEMBL3282010

Cc1ccc(C(N)Cc2ccccc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.52
TAAR1 Q96RJ0 2/20 0.52
MAOA P21397 1/20 0.52
SLC6A4 P31645 1/20 0.52
SLC6A3 Q01959 1/20 0.52
SIGMAR1 Q99720 1/20 0.52
CYP2A6 P11509 1/20 0.52
ADORA2A P29274 1/20 0.52
ADORA1 P30542 1/20 0.52
CYP2D6 P10635 2/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2C19 P33261 1/20 0.52
EPHX1 P07099 1/20 0.50
TACR1 P25103 2/20 0.45
LMNA P02545 1/20 0.44
POLB P06746 1/20 0.44
ANPEP P15144 1/20 0.44
CNR1 P21554 1/20 0.44
CNR2 P34972 1/20 0.44
PRKACA P17612 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2785511 0.92 CYP2D6 (0.52) SLC6A2TAAR1MAOASLC6A4SLC6A3
SCHEMBL924299 0.92 CYP2D6 (0.52) SLC6A2TAAR1MAOASLC6A4SLC6A3
SCHEMBL2333573 0.92 CYP2D6 (0.52) SLC6A2TAAR1MAOASLC6A4SLC6A3
SCHEMBL248882 0.92 CYP2D6 (0.52) SLC6A2TAAR1MAOASLC6A4SLC6A3
SCHEMBL10804153 0.90 CYP1A2 (0.62) SLC6A2TAAR1SLC6A4SLC6A3CYP2A6
SCHEMBL12706002 0.90 CYP1A2 (0.62) SLC6A2TAAR1SLC6A4SLC6A3CYP2A6
SCHEMBL468022 0.85 EPHX1 (0.61) SLC6A2TAAR1MAOASLC6A4SLC6A3
SCHEMBL3451169 0.85 EPHX1 (0.61) SLC6A2TAAR1MAOASLC6A4SLC6A3
SCHEMBL272604 0.85 EPHX1 (0.61) SLC6A2TAAR1MAOASLC6A4SLC6A3
Hydrochloric Acid SCHEMBL28839661 0.83 EPHX1 (0.58) SLC6A2TAAR1MAOASLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0092194-B1 METHOD OF OBTAINING OPTICALLY ACTIVE HALF ESTERS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-07-08 EP claimed
EP-0093511-B1 METHOD FOR PRODUCING AND OPTICALLY ACTIVE 2,2-DIMETHYLCYCLOPROPANECARBOXYLIC ACID SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-09-24 EP claimed
US-4542235-A Method for producing an optically active 2,2-dimethylcyclopropanecarboxylic acid SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-09-17 US claimed
EP-0093511-A1 Method for producing and optically active 2,2-dimethylcyclopropanecarboxylic acid SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-11-09 EP claimed
EP-0092194-A1 Method of obtaining optically active half esters SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-10-26 EP claimed
US-3970700-A Racemization of optically active amines SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-07-20 US claimed
US-3954870-A RANEY NICKEL CATALYST SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-05-04 US claimed
JP-55092343-A None JP disclosed
EP-2018364-B1 THERAPEUTIC FLUOROETHYL UREAS ALLERGAN INC (US) 2013-08-21 EP disclosed
US-7709507-B2 Therapeutic fluoroethyl ureas ALLERGAN, INC. (US) 2010-05-04 US disclosed
US-20070270498-A1 THERAPEUTIC FLUOROETHYL UREAS ALLERGAN, INC. 2007-11-22 US disclosed
EP-0092194-B1 METHOD OF OBTAINING OPTICALLY ACTIVE HALF ESTERS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-07-08 EP disclosed
EP-0093511-B1 METHOD FOR PRODUCING AND OPTICALLY ACTIVE 2,2-DIMETHYLCYCLOPROPANECARBOXYLIC ACID SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-09-24 EP disclosed
EP-0093511-A1 Method for producing and optically active 2,2-dimethylcyclopropanecarboxylic acid SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-11-09 EP disclosed
EP-0092194-A1 Method of obtaining optically active half esters SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-10-26 EP disclosed
US-4246424-A IN PRESENCE OF ALKALI METAL AND POLYCYCLIC AROMATIC HYDROCARBON SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-01-20 US disclosed
JP-S5592343-A PREPARATION OF OPTICALLY ACTIVE SUBSTITUTED ISOVALERIC ACID KATSUTA YOSHIO 1980-07-12 JP disclosed
US-4158016-A CONTACTING WITH AN ALKALI METAL POLYCYCLIC AROMATIC HYDROCARBON CATALYST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1979-06-12 US disclosed
US-3970700-A Racemization of optically active amines SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-07-20 US disclosed
US-3954870-A RANEY NICKEL CATALYST SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070270498-A1 THERAPEUTIC FLUOROETHYL UREAS SLC14A1, MAPT, UTS2R SLC6A2 716/4885TAAR1 2600/4885MAOA 3805/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.