Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.66 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | PLK4 | O00444 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3281177 | 0.85 | DPP4 (0.47) | DPP4DPP8TAAR1GRIN2DGRIN3B | |
| SCHEMBL3281088 | 0.82 | KCNA5 (0.47) | DPP4DPP8SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1467599 | 0.75 | TAAR1 (0.52) | DPP4TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9586712 | 0.74 | DPP4 (0.38) | DPP4SLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL20161327 | 0.74 | NPC1 (0.38) | DPP4DPP8TAAR1SLC6A2SLC6A4 | |
| SCHEMBL8867023 | 0.74 | SLC6A2 (0.66) | DPP4TAAR1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL12706272 | 0.74 | TAAR1 (0.47) | DPP4TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4749345 | 0.74 | DPP4 (0.42) | DPP4TAAR1GRIN2DGRIN3BGRIN1 | |
| Bromide SCHEMBL6906999 | 0.74 | TAAR1 (0.50) | DPP4TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3674139 | 0.73 | TAAR1 (0.54) | DPP4TAAR1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018364-B1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN INC (US) | 2013-08-21 | — | — | EP | disclosed |
| US-7709507-B2 | Therapeutic fluoroethyl ureas | ALLERGAN, INC. (US) | 2010-05-04 | — | — | US | disclosed |
| US-20070270498-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. | 2007-11-22 | — | — | US | disclosed |
| CN-86103621-A | The method of the sulphonamide of preparation agriculturally useful | — | 1986-12-10 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070270498-A1 | THERAPEUTIC FLUOROETHYL UREAS | SLC14A1, MAPT, UTS2R | DPP4 2022/4885DPP8 2432/4885TAAR1 2600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.