SCHEMBL328269

SCHEMBL328269

CNC(OC)OC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8311602 0.70
SCHEMBL25987663 0.67
SCHEMBL40163 0.64
SCHEMBL25939414 0.64
SCHEMBL14532197 0.64
SCHEMBL20038146 0.64
SCHEMBL24013005 0.62
SCHEMBL10088069 0.62
SCHEMBL27489019 0.62
SCHEMBL5932164 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111620764-A Selective ether bond breaking method of aryl alkyl ether 荆楚理工学院 2020-09-04 CN claimed
CN-108864088-B The preparation method of novel isoquinoline drug molecule with antibacterial activity 上海万巷制药有限公司 2019-10-11 CN claimed
EP-4745134-A1 PROTEIN ARGINASE METHYLTRANSFERASE-5 INHIBITOR AND MEDICAL USE THEREOF Jiangsu Yahong Meditech Co., Ltd. (CN) 2026-05-20 EP disclosed
WO-2025137231-A1 METHODS AND INTERMEDIATES FOR PREPARING THERAPEUTIC COMPOUNDS GILEAD SCIENCES, INC. (US) 2025-06-26 WO disclosed
CN-113527305-B Pharmaceutically acceptable salts of quinoline TGF-beta 1 inhibitors and preparation method thereof 南京圣和药物研发有限公司 2025-06-24 CN disclosed
CN-113527306-B Crystal forms of quinoline TGF-beta 1 inhibitor 南京圣和药物研发有限公司 2025-06-24 CN disclosed
CN-120152977-A Method for purifying compounds AC免疫有限公司 2025-06-13 CN disclosed
CN-115209952-B Substituted pyrazolopyrimidines and use thereof 维基分析有限公司 2025-05-30 CN disclosed
CN-120077046-A Triazole-substituted imidazo [1,2-A ] pyrimidines as CGAS inhibitors 葛兰素史密斯克莱知识产权发展有限公司 2025-05-30 CN disclosed
CN-114901280-B MrgprX2 antagonists and uses thereof 德米拉公司 2025-05-27 CN disclosed
CN-119923398-A Cyclic compounds and methods of use thereof 薛定谔公司 2025-05-02 CN disclosed
WO-1996006950-A9 REDUCTION OF NONSPECIFIC HYBRIDIZATION BY USING NOVEL BASE-PAIRING SCHEMES 1997-05-09 WO disclosed
WO-1996006950-A1 REDUCTION OF NONSPECIFIC HYBRIDIZATION BY USING NOVEL BASE-PAIRING SCHEMES CHIRON CORPORATION (US) 1996-03-07 WO disclosed
CN-1027067-C Production of novel 5-fluoronicotinic acids or derivatives thereof TOYAMA CHEMICAL CO LTD (JP) 1994-12-21 CN disclosed
CN-1019012-B Process for preparing 1-substituted phenyl-1, 4-dihydro-4-oxo-1, 8-naphthyridine derivatives TOYAMA CHEMICAL CO LTD (JP) 1992-11-11 CN disclosed
CN-1054975-A Produce the method for new 5-fluorine nicotinic acid or derivatives thereof or its carboxyl response activity derivant and their salt TOYAMA CHEMICAL CO LTD (JP) 1991-10-02 CN disclosed
EP-0277520-A2 Parasiticide on a pyrimidine derivative basis BAYER AG (DE) 1988-08-10 EP disclosed
EP-0104860-B1 1-PHENYL-2(1H,3H)-INDOLONE PSYCHO-THERAPEUTIC AGENTS PFIZER INC. (US) 1987-03-18 EP disclosed
CN-86100879-A Novel process for preparing 1-substituted aryl-1, 4-dihydro-4-oxo-1, 8-naphthyridine derivatives and intermediates thereof 1986-12-17 CN disclosed
EP-0014454-B1 PROCESS AND INTERMEDIATES FOR THE PREPARATION OF 2-BENZAZEPINE DERIVATIVES F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1982-09-22 EP disclosed