Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 9/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10038925 | 1.00 | PDK2 (0.41) | PDK2ESR1ESR2PTPRCELANE | |
| SCHEMBL22053434 | 1.00 | PDK2 (0.41) | PDK2ESR1ESR2PTPRCELANE | |
| SCHEMBL14183694 | 1.00 | PDK2 (0.41) | PDK2ESR1ESR2PTPRCELANE | |
| SCHEMBL10820310 | 1.00 | PDK2 (0.41) | PDK2ESR1ESR2PTPRCELANE | |
| SCHEMBL19167936 | 0.98 | PDK2 (0.40) | PDK2ESR1ESR2PTPRCELANE | |
| SCHEMBL17816748 | 0.98 | PDK2 (0.40) | PDK2ESR1ESR2PTPRCELANE | |
| SCHEMBL19166053 | 0.98 | PDK2 (0.40) | PDK2ESR1ESR2PTPRCELANE | |
| SCHEMBL14329490 | 0.97 | PDK2 (0.45) | PDK2ESR1ESR2PTPRCELANE | |
| SCHEMBL12325035 | 0.97 | PDK2 (0.43) | PDK2ESR1ESR2PTPRCELANE | |
| SCHEMBL12249764 | 0.97 | PDK2 (0.43) | PDK2ESR1ESR2PTPRCELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7714145-B2 | 2-2′-disubstituted 9,9′-spirobifluorene-base triaryldiamines and their application | Wong, Ken-Tsung (TW) | 2010-05-11 | — | — | US | disclosed |
| US-7714145-B2 | 2-2′-disubstituted 9,9′-spirobifluorene-base triaryldiamines and their application | Wong, Ken-Tsung (TW) | 2010-05-11 | — | — | US | disclosed |
| US-7714145-B2 | 2-2′-disubstituted 9,9′-spirobifluorene-base triaryldiamines and their application | Wong, Ken-Tsung (TW) | 2010-05-11 | — | — | US | disclosed |
| US-20070262703-A1 | 2,2'-Disubstituted 9,9'-Spirobifluorene-based Triaryldiamines and Their Application | Wong, Ken-Tsung (TW) | 2007-11-15 | — | — | US | disclosed |
| US-20070262703-A1 | 2,2'-Disubstituted 9,9'-Spirobifluorene-based Triaryldiamines and Their Application | Wong, Ken-Tsung (TW) | 2007-11-15 | — | — | US | disclosed |
| US-20070262703-A1 | 2,2'-Disubstituted 9,9'-Spirobifluorene-based Triaryldiamines and Their Application | Wong, Ken-Tsung (TW) | 2007-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070262703-A1 | 2,2'-Disubstituted 9,9'-Spirobifluorene-based Triaryldiamines and Their Application | SLC9B2, SLC9A2, SLC29A2 | PDK2 205/4885ESR1 4008/4885ESR2 1987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.