Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | VDR | P11473 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | CA9 | Q16790 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | PREP | P48147 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3283533 | 1.00 | HSP90AA1 (0.38) | HSP90AA1HSP90AB1VDRCA12CA1 | |
| SCHEMBL3283542 | 1.00 | HSP90AA1 (0.38) | HSP90AA1HSP90AB1VDRCA12CA1 | |
| SCHEMBL3279193 | 0.87 | VDR (0.38) | HSP90AA1HSP90AB1VDRCA12CA1 | |
| SCHEMBL3279186 | 0.87 | VDR (0.38) | HSP90AA1HSP90AB1VDRCA12CA1 | |
| SCHEMBL3279192 | 0.87 | VDR (0.38) | HSP90AA1HSP90AB1VDRCA12CA1 | |
| SCHEMBL6753237 | 0.87 | HSP90AA1 (0.38) | HSP90AA1HSP90AB1VDRCA12CA1 | |
| SCHEMBL3280525 | 0.84 | HSP90AA1 (0.40) | HSP90AA1HSP90AB1CA12CA1CA9 | |
| SCHEMBL3280516 | 0.84 | HSP90AA1 (0.40) | HSP90AA1HSP90AB1CA12CA1CA9 | |
| SCHEMBL3280523 | 0.84 | HSP90AA1 (0.40) | HSP90AA1HSP90AB1CA12CA1CA9 | |
| SCHEMBL3280453 | 0.83 | HSP90AA1 (0.36) | HSP90AA1HSP90AB1VDRCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700657-B2 | Vitamin D analogs | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-04-20 | — | — | US | disclosed |
| US-20040224929-A1 | Novel vitamin D analogs | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-11-11 | — | — | US | disclosed |