SCHEMBL3283992

SCHEMBL3283992

Oc1c2c(c(O)c3c1CCCC3)CCCC2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 1/20 0.38
BAD Q92934 1/20 0.38
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
ACHE P22303 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C19 P33261 1/20 0.30
TSHR P16473 1/20 0.30
CASP1 P29466 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
ALOX15 P16050 1/20 0.30
ALOX12 P18054 1/20 0.30
MPI P34949 1/20 0.30
HTT P42858 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10533533 0.80 BCL2L1 (0.31) BCL2L1BAD
SCHEMBL14283980 0.79 MEN1 (0.35) BCL2L1BADMEN1KMT2AACHE
SCHEMBL6049113 0.73 KDM4E (0.48) BCL2L1BADMEN1KMT2AACHE
SCHEMBL9984719 0.71 SMN1; SMN2 (0.40) BCL2L1BADMEN1KMT2AACHE
SCHEMBL1047907 0.71 MEN1 (0.35) MEN1KMT2ACASP1KDM4EALDH1A1
SCHEMBL14283979 0.69 KDM4E (0.40) BCL2L1BADMEN1KMT2AACHE
SCHEMBL6934942 0.67 KMT2A (0.33) BCL2L1BADMEN1KMT2AACHE
SCHEMBL3283307 0.67 BCL2L1 (0.56) BCL2L1BADMEN1KMT2ACYP1A2
SCHEMBL15747949 0.65 TSHR (0.35) BCL2L1BADKMT2AACHETSHR
SCHEMBL689737 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7714175-B2 Production method of aromatic hydroxide SUMITOMO CHEMICAL COMPANY, LIMITED (JO) 2010-05-11 US disclosed
US-20090318736-A1 Production method of aromatic hydroxide SUMITOMO CHEMICAL COMPANY, LIMITED 2009-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090318736-A1 Production method of aromatic hydroxide PAH, AHR, HRH3 BCL2L1 2390/4885BAD 3662/4885MEN1 2599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.