SCHEMBL3283307

SCHEMBL3283307

Oc1ccc(O)c2c1CCCC2

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 1/20 0.56
BAD Q92934 1/20 0.56
HSD11B1 P28845 1/20 0.40
HSD17B2 P37059 1/20 0.40
AR P10275 1/20 0.39
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 2/20 0.38
GAA P10253 2/20 0.38
GLA P06280 1/20 0.38
HPGD P15428 1/20 0.38
MAOA P21397 1/20 0.38
MAPK1 P28482 1/20 0.38
CASP1 P29466 1/20 0.38
CASP7 P55210 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C19 P33261 1/20 0.35
MAOB P27338 1/20 0.35
PIM1 P11309 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10802712 0.93 BCL2L1 (0.50) BCL2L1BADHSD11B1HSD17B2AR
SCHEMBL12909320 0.87 BCL2L1 (0.46) BCL2L1BADHSD11B1HSD17B2AR
SCHEMBL6711459 0.86 BCL2L1 (0.42) BCL2L1BADARKDM4EALDH1A1
SCHEMBL12118828 0.84 BCL2L1 (0.45) BCL2L1BADHSD11B1HSD17B2AR
SCHEMBL10773279 0.84 BCL2L1 (0.45) BCL2L1BADHSD11B1HSD17B2AR
SCHEMBL19679258 0.84 BCL2L1 (0.45) BCL2L1BADHSD11B1HSD17B2AR
SCHEMBL3975159 0.84 BCL2L1 (0.45) BCL2L1BADHSD11B1HSD17B2AR
SCHEMBL9230304 0.84 BCL2L1 (0.45) BCL2L1BADHSD11B1HSD17B2AR
SCHEMBL4424942 0.84 BCL2L1 (0.45) BCL2L1BADHSD11B1HSD17B2AR
SCHEMBL1008430 0.81 MAOA (0.44) BCL2L1BADARKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117624076-A Heterocyclic compounds for liquid crystals 默克专利股份有限公司 2024-03-01 CN claimed
CN-117043304-A Aromatic isothiocyanates 默克专利股份有限公司 2023-11-10 CN claimed
CN-116601265-A Aromatic isothiocyanates 默克专利股份有限公司 2023-08-15 CN claimed
CN-116507695-A Aromatic isothiocyanates 默克专利股份有限公司 2023-07-28 CN claimed
CN-116490591-A Aromatic isothiocyanates 默克专利股份有限公司 2023-07-25 CN claimed
WO-1996015112-A1 AZEPINE SYNTHESIS VIA A DIELS-ALDER REACTION ACEA PHARMACEUTICALS, INC. (US) 1996-05-23 WO claimed
US-5476933-A Condensation, ring expansion STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION, ACTING FOR AND ON BEHALF OF THE OREGON HEALTH SCIENCES UNIVERSITY AND THE UNIVERSITY OF OREGON (US) 1995-12-19 US claimed
US-4501898-A Photographic development inhibitor (1H- or 2H-) indazolyl hydroquinone derivatives FUJI PHOTO FILM CO., LTD. (JP) 1985-02-26 US claimed
US-4332878-A USING A HYDROQUINONE DERIVATIVE IN THE SILVER HALIDE EMULSION LAYER AND DEVELOPING IN THE PRESENCE OF A HYDRAZINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1982-06-01 US claimed
CN-117624076-A Heterocyclic compounds for liquid crystals 默克专利股份有限公司 2024-03-01 CN disclosed
CN-117043304-A Aromatic isothiocyanates 默克专利股份有限公司 2023-11-10 CN disclosed
CN-116601265-A Aromatic isothiocyanates 默克专利股份有限公司 2023-08-15 CN disclosed
CN-116507695-A Aromatic isothiocyanates 默克专利股份有限公司 2023-07-28 CN disclosed
CN-116490591-A Aromatic isothiocyanates 默克专利股份有限公司 2023-07-25 CN disclosed
US-4501898-A Photographic development inhibitor (1H- or 2H-) indazolyl hydroquinone derivatives FUJI PHOTO FILM CO., LTD. (JP) 1985-02-26 US disclosed
US-4477554-A SILVER HALIDE EMULSION CONTAINING QUINOID DYE-RELEASING COMPOUND AGFA-GEVAERT, N.V. (BE) 1984-10-16 US disclosed
US-4459351-A Photographic element and process employed combination of surface and internal latent image silver halide EASTMAN KODAK COMPANY (US) 1984-07-10 US disclosed
EP-0109701-A1 Diffusion transfer material AGFA-GEVAERT N.V. (BE) 1984-05-30 EP disclosed
US-4345024-A A 3-INDAZOL-1 OR 2-YL HYDROQUINONE DERIVATIVE IN A PHOTOSENSITIVE SILVER HALIDE EMULSION; COLOR FILMS; BLACK AND WHITE PHOTOGRAPHY FUJI PHOTO FILM CO., LTD. (JP) 1982-08-17 US disclosed
US-4332878-A USING A HYDROQUINONE DERIVATIVE IN THE SILVER HALIDE EMULSION LAYER AND DEVELOPING IN THE PRESENCE OF A HYDRAZINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1982-06-01 US disclosed