Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.71 |
| ▸ | TSHR | P16473 | 4/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylene Chloride SCHEMBL1594385 | 0.97 | ALDH1A1 (0.67) | ALDH1A1TSHRTDP1HSD17B10LMNA | |
| SCHEMBL523 | 0.84 | — | — | |
| SCHEMBL1331977 | 0.84 | — | — | |
| SCHEMBL9866292 | 0.84 | — | — | |
| SCHEMBL1331774 | 0.84 | — | — | |
| SCHEMBL1330344 | 0.84 | — | — | |
| SCHEMBL5305593 | 0.84 | ALDH1A1 (1.00) | ALDH1A1TSHRTDP1HSD17B10LMNA | |
| SCHEMBL11127931 | 0.82 | ALDH1A1 (0.56) | ALDH1A1TSHRTDP1HSD17B10LMNA | |
| SCHEMBL28899250 | 0.81 | ALDH1A1 (0.77) | ALDH1A1TSHRTDP1HSD17B10LMNA | |
| SCHEMBL7287534 | 0.81 | ALDH1A1 (0.77) | ALDH1A1TSHRTDP1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108672-B | Condensed five rings imdazole derivatives | UCB生物制药私人有限公司 | 2019-11-08 | — | — | CN | disclosed |
| CN-105744936-B | Substituted quinolizine derivatives useful as HIV integrase inhibitors | 默沙东公司 | 2019-07-30 | — | — | CN | disclosed |
| CN-106397295-B | A kind of method that solid acid continuous load is catalyzed heteroaromatic compounds 2- acylation | 凯莱英医药集团（天津）股份有限公司 | 2019-04-23 | — | — | CN | disclosed |
| CN-109369390-A | The continuous preparation method of resveratrol triacetate | 杭州师范大学 | 2019-02-22 | — | — | CN | disclosed |
| CN-105793266-B | Spiro-oxazolones | 豪夫迈·罗氏有限公司 | 2019-02-12 | — | — | CN | disclosed |
| CN-104903320-B | Nitrogen-containing heterocycle compound or its salt | 富士胶片株式会社 | 2018-11-13 | — | — | CN | disclosed |
| CN-107936039-A | Tricyclic condensed thiophene derivant as JAK inhibitor | 因赛特公司 | 2018-04-20 | — | — | CN | disclosed |
| CN-104918945-B | Tricyclic fused thiophene derivatives as JAK inhibitors | 因赛特公司 | 2018-01-05 | — | — | CN | disclosed |
| CN-107108672-A | The five rings imdazole derivatives of fusion | UCB生物制药私人有限公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-106397295-A | 2-branch acylation method of solid acid continuous loaded catalyzed aromatic heterocyclic compound | 凯莱英医药集团（天津）股份有限公司 | 2017-02-15 | — | — | CN | disclosed |
| CN-103554095-A | Novel acetyl-coa carboxylase (acc) inhibitors and their use in diabetes, obesity and metabolic syndrome | ABBVIE INC | 2014-02-05 | — | — | CN | disclosed |
| CN-102159580-B | Process for preparing 1,6:2, 3-dianhydro-beta-D-mannopyranose | SANOFI AVENTIS | 2014-01-01 | — | — | CN | disclosed |
| CN-103242413-A | Lupane triterpenoid derivative and pharmaceutical application thereof | LU FENG | 2013-08-14 | — | — | CN | disclosed |
| CN-102159580-A | Process for preparing 1,6:2, 3-dianhydro-beta-D-mannopyranose | SANOFI AVENTIS | 2011-08-17 | — | — | CN | disclosed |
| US-7714146-B2 | Azulene-oxindole compounds as multiple-kinase inhibitors and useful as anticancer agents | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2010-05-11 | — | — | US | disclosed |
| US-20080125590-A1 | Azulene compounds | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2008-05-29 | — | — | US | disclosed |
| CN-1315936-A | Compounds and compositions for delivery of active agents | EMISPHERE TECH INC (US) | 2001-10-03 | — | — | CN | disclosed |
| WO-2001002558-A1 | PROBE FOR ANALYSIS OF NUCLEIC ACIDS | LIGHTUP TECHNOLOGIES AB (SE) | 2001-01-11 | — | — | WO | disclosed |
| US-4111924-A | REACTION WITH MERCURIC ACETATE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1978-09-05 | — | — | US | disclosed |
| US-4086220-A | GASTRIC ANTISECRETORY AGENTS | G. D. SEARLE & CO. (US) | 1978-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080125590-A1 | Azulene compounds | AZI2, PRMT5, BRCA1 | ALDH1A1 421/4885TSHR 313/4885TDP1 3150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.