Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | FDPS | P14324 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.44 |
| ▸ | PPARG | P37231 | 6/20 | 0.44 |
| ▸ | PPARD | Q03181 | 6/20 | 0.44 |
| ▸ | PPARA | Q07869 | 6/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8466412 | 1.00 | SMPD1 (0.45) | SMPD1CES2FDPSGPR84PPARG | |
| SCHEMBL7623878 | 1.00 | SMPD1 (0.45) | SMPD1CES2FDPSGPR84PPARG | |
| SCHEMBL7619946 | 1.00 | SMPD1 (0.45) | SMPD1CES2FDPSGPR84PPARG | |
| SCHEMBL658156 | 1.00 | SMPD1 (0.45) | SMPD1CES2FDPSGPR84PPARG | |
| SCHEMBL249486 | 1.00 | SMPD1 (0.45) | SMPD1CES2FDPSGPR84PPARG | |
| SCHEMBL7617795 | 1.00 | SMPD1 (0.45) | SMPD1CES2FDPSGPR84PPARG | |
| SCHEMBL8464966 | 1.00 | SMPD1 (0.45) | SMPD1CES2FDPSGPR84PPARG | |
| Hydrochloric Acid SCHEMBL11771276 | 0.98 | SMPD1 (0.44) | SMPD1CES2FDPSGPR84PPARG | |
| SCHEMBL27446363 | 0.98 | SMPD1 (0.44) | SMPD1CES2FDPSGPR84PPARG | |
| Ammonia Solution, Strong SCHEMBL28996637 | 0.98 | SMPD1 (0.44) | SMPD1CES2FDPSGPR84PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828768-B1 | HOMOPOLYMERS AND COPOLYMERS OF CATIONICALLY POLYMERIZABLE MONOMERS AND METHOD OF THEIR PREPARATION | GOODRICH CO B F (US) | 2001-04-18 | — | — | EP | claimed |
| CN-117886793-A | Method for preparing R-lipoic acid by chiral ion exchange chromatography | 江苏同禾药业有限公司 | 2024-04-16 | — | — | CN | disclosed |
| WO-2023071328-A1 | METHOD FOR SYNTHESIZING 8-AMINO-1-{[2-(TRIMETHYLSILYL)ETHOXY]METHOXY}OCTANE-3-ONE | 苏州富士莱医药股份有限公司 | 2023-05-04 | — | — | WO | disclosed |
| CN-115716817-A | Preparation method of 6,8-cyclotrithiooctanoic acid | 国药集团威奇达药业有限公司 | 2023-02-28 | — | — | CN | disclosed |
| CN-115093392-A | Preparation method of R-lipoic acid | 苏州富士莱医药股份有限公司 | 2022-09-23 | — | — | CN | disclosed |
| CN-113185494-B | Preparation method of R-lipoic acid | 苏州富士莱医药股份有限公司 | 2022-04-15 | — | — | CN | disclosed |
| CN-113429386-B | Synthetic method of R-lipoic acid | 苏州富士莱医药股份有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-113717210-B | Synthesis method of 8-amino-1- { [2- (trimethylsilyl) ethoxy ] methoxy } octane-3-one | 苏州富士莱医药股份有限公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-113735895-A | Preparation method of lipoic acid intermediate | 苏州富士莱医药股份有限公司 | 2021-12-03 | — | — | CN | disclosed |
| CN-113717210-A | Synthesis method of 8-amino-1- { [2- (trimethylsilyl) ethoxy ] methoxy } octane-3-one | 苏州富士莱医药股份有限公司 | 2021-11-30 | — | — | CN | disclosed |
| US-20070167343-A1 | neutralized salt including alkylbenzenesulphonates (toluenesulfonic acid guanidine salt, toluenesulfonic acid DBU salt, toluenesulfonic acid DBN salt) for cleaning electonics | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2007-07-19 | — | — | US | disclosed |
| US-20070015926-A1 | Method of preparing R-(+)-alpha-lipoic acid and its salt | NANJING RALLY BIOCHEMICAL INC. | 2007-01-18 | — | — | US | disclosed |
| EP-0790824-B1 | 2,2-DICHLOROALKANE CARBOXYLIC ACIDS, PROCESS FOR PREPARING THE SAME, MEDICAMENT CONTAINING THE SAME, AND USE THEREOF FOR TREATING INSULIN RESISTANCE | ROCHE DIAGNOSTICS GMBH (DE) | 2002-02-06 | — | — | EP | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| US-5968982-A | TREATMENT OF DIABETES | ROCHE DIAGNOSTICS GMBH (DE) | 1999-10-19 | — | — | US | disclosed |
| EP-0790824-A1 | 2,2-DICHLOROALKANE CARBOXYLIC ACIDS, PROCESS FOR PREPARING THE SAME, MEDICAMENT CONTAINING THE SAME, AND USE THEREOF FOR TREATING INSULIN RESISTANCE | Roche Diagnostics GmbH (DE) | 1997-08-27 | — | — | EP | disclosed |
| WO-1996015784-A2 | 2,2-DICHLOROALKANE CARBOXYLIC ACIDS, PROCESS FOR PREPARING THE SAME, MEDICAMENT CONTAINING THE SAME, AND USE THEREOF FOR TREATING INSULIN RESISTANCE | BOEHRINGER MANNHEIM GMBH (DE) | 1996-05-30 | — | — | WO | disclosed |
| US-4938898-A | Chlorination of acty chloride | THE PROCTER & GAMBLE COMPANY (US) | 1990-07-03 | — | — | US | disclosed |
| EP-0167202-B1 | ALPHA CHLORINIATION PROCESS EMPLOYING FOOD GRADE ANTIOXIDANTS, OXYGEN OR CYANOQUINONES | THE PROCTER & GAMBLE COMPANY (US) | 1990-01-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015926-A1 | Method of preparing R-(+)-alpha-lipoic acid and its salt | RALA, LIPA, DHCR7 | SMPD1 3518/4885CES2 1455/4885FDPS 1404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.