SCHEMBL658156

SCHEMBL658156

CCCCCCCCCCCCCCCCC(Cl)(Cl)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMPD1 P17405 2/20 0.45
CES2 O00748 1/20 0.45
FDPS P14324 1/20 0.45
GPR84 Q9NQS5 7/20 0.44
PPARG P37231 6/20 0.44
PPARD Q03181 6/20 0.44
PPARA Q07869 6/20 0.44
HDAC11 Q96DB2 5/20 0.44
TSHR P16473 4/20 0.44
ALDH1A1 P00352 2/20 0.44
TLR2 O60603 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
FABP4 P15090 2/20 0.44
PTPN1 P18031 2/20 0.44
SLC22A6 Q4U2R8 1/20 0.44
SLC22A8 Q8TCC7 1/20 0.44
MEN1 O00255 1/20 0.44
ESR1 P03372 1/20 0.44
ALOX15 P16050 1/20 0.44
PDE4A P27815 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8466412 1.00 SMPD1 (0.45) SMPD1CES2FDPSGPR84PPARG
SCHEMBL7623878 1.00 SMPD1 (0.45) SMPD1CES2FDPSGPR84PPARG
SCHEMBL3284980 1.00 SMPD1 (0.45) SMPD1CES2FDPSGPR84PPARG
SCHEMBL7619946 1.00 SMPD1 (0.45) SMPD1CES2FDPSGPR84PPARG
SCHEMBL249486 1.00 SMPD1 (0.45) SMPD1CES2FDPSGPR84PPARG
SCHEMBL7617795 1.00 SMPD1 (0.45) SMPD1CES2FDPSGPR84PPARG
SCHEMBL8464966 1.00 SMPD1 (0.45) SMPD1CES2FDPSGPR84PPARG
Hydrochloric Acid SCHEMBL11771276 0.98 SMPD1 (0.44) SMPD1CES2FDPSGPR84PPARG
SCHEMBL27446363 0.98 SMPD1 (0.44) SMPD1CES2FDPSGPR84PPARG
Ammonia Solution, Strong SCHEMBL28996637 0.98 SMPD1 (0.44) SMPD1CES2FDPSGPR84PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107261148-A Methylphenidate prodrug, its preparation and application 凯姆制药公司 2017-10-20 CN claimed
CN-103826633-A Methylphenidate prodrugs, methods of making and using the same KEMPHARM INC 2014-05-28 CN claimed
EP-3911723-B1 TRACTION FLUIDS LUBRIZOL CORP (US) 2024-05-08 EP disclosed
CN-113302266-B Traction fluid 路博润公司 2023-02-24 CN disclosed
US-20220127539-A1 Traction Fluids LUBRIZOL CORP (US) 2022-04-28 US disclosed
CN-107261148-B Methylphenidate prodrugs, methods of making and using the same 凯姆制药公司 2021-07-13 CN disclosed
EP-2401348-B1 LUBRICATING COMPOSITIONS CONTAINING THE REACTION PRODUCT OF AN AROMATIC AMINE AND A CARBOXYLIC FUNCTIONALISED POLYMER AND DISPERSANT LUBRIZOL CORP (US) 2017-11-15 EP disclosed
EP-2431448-B1 Lubricating compositions containing the reaction product of an aromatic amine and a carboxylic functionalised polymer and dispersant LUBRIZOL CORP (US) 2017-11-15 EP disclosed
CN-107261148-A Methylphenidate prodrug, its preparation and application 凯姆制药公司 2017-10-20 CN disclosed
CN-103826633-B Methylphenidate prodrugs, methods of making and using the same 凯姆制药公司 2017-05-24 CN disclosed
US-9644167-B2 Lubricating compositions containing a carboxylic functionalised polymer and dispersant THE LUBRIZOL CORPORATION (US) 2017-05-09 US disclosed
EP-0094261-A2 One-component moisture curable urethane coating system The Lubrizol Corporation (US) 1983-11-16 EP disclosed
EP-0094196-A2 Two-component urethane coating system The Lubrizol Corporation (US) 1983-11-16 EP disclosed
EP-0087835-A2 Process for alpha halogenating alkyl carboxylic acids and catalyst composition for use therein THE PROCTER & GAMBLE COMPANY (US) 1983-09-07 EP disclosed
US-4345045-A HEAT RESISTANCE DART INDUSTRIES, INC. (US) 1982-08-17 US disclosed
US-4278610-A SALT FORMATION, COMPLEXING NATIONAL RESEARCH LABORATORIES (US) 1981-07-14 US disclosed
EP-0008174-A1 Method of making an organic metal salt or complex NATIONAL RESEARCH LABORATORIES (US) 1980-02-20 EP disclosed
US-4046941-A PRESSURE SENSITIVE COPYING SANKO CHEMICAL COMPANY LTD. (JA) 1977-09-06 US disclosed
US-3945931-A Utilization of amido-acids for the production of aqueous fluids for the working of metals AQUILA S.P.A. (IT) 1976-03-23 US disclosed
US-3945955-A OPEN-CELLED FOAMS BY MECHANICAL WHIPPING DIAMOND SHAMROCK CORPORATION (US) 1976-03-23 US disclosed