Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 12/20 | 0.53 |
| ▸ | THRB | P10828 | 12/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6696145 | 0.81 | THRA (0.57) | THRATHRB | |
| SCHEMBL6695589 | 0.80 | THRA (0.51) | THRATHRB | |
| SCHEMBL6695019 | 0.80 | THRA (0.47) | THRATHRB | |
| SCHEMBL10274429 | 0.80 | THRA (0.65) | THRATHRB | |
| SCHEMBL6695024 | 0.80 | THRA (0.50) | THRATHRB | |
| SCHEMBL6690819 | 0.79 | THRA (0.55) | THRATHRB | |
| SCHEMBL6694222 | 0.79 | THRA (0.60) | THRATHRB | |
| SCHEMBL328490 | 0.79 | THRA (0.53) | THRATHRB | |
| SCHEMBL6693202 | 0.78 | THRA (0.54) | THRATHRB | |
| SCHEMBL6694746 | 0.78 | THRA (0.54) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2428516-A1 | Novel phosphorus-containing thyromimetics | Metabasis Therapeutics, Inc. (US) | 2012-03-14 | — | — | EP | disclosed |