SCHEMBL3285649

SCHEMBL3285649

CCC(C)c1ccc(NCCNc2ccc(C(C)CC)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.51
NPSR1 Q6W5P4 2/20 0.49
MAPT P10636 5/20 0.48
ALDH1A1 P00352 4/20 0.47
GAA P10253 2/20 0.47
CYP2C9 P11712 2/20 0.44
NPC1 O15118 6/20 0.44
RAB9A P51151 6/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
NFKB1 P19838 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
TP53 P04637 2/20 0.43
LMNA P02545 1/20 0.43
ALOX12 P18054 1/20 0.43
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
HPGD P15428 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4981119 0.92 TSHR (0.49) TSHRNPSR1MAPTALDH1A1GAA
SCHEMBL12624361 0.87 TSHR (0.51) TSHRNPSR1MAPTALDH1A1GAA
SCHEMBL11935537 0.86 SLC7A5 (0.45) TSHRNPSR1MAPTALDH1A1GAA
SCHEMBL598140 0.81 ALDH1A1 (0.52) TSHRNPSR1MAPTALDH1A1GAA
SCHEMBL4089391 0.80 TSHR (0.53) TSHRNPSR1MAPTALDH1A1GAA
SCHEMBL22338023 0.80 TSHR (0.53) TSHRNPSR1MAPTALDH1A1GAA
SCHEMBL16745695 0.80 TSHR (0.50) TSHRNPSR1MAPTALDH1A1GAA
SCHEMBL2064181 0.79 MAPT (0.54) MAPTALDH1A1GAASMN1; SMN2NFKB1
SCHEMBL16745698 0.79 TSHR (0.49) TSHRNPSR1MAPTALDH1A1NPC1
SCHEMBL14216272 0.78 ALDH1A1 (0.52) TSHRNPSR1MAPTALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7713444-B2 Mixtures of sterically hindered amines for the stabilisation of polymers 3V SIGMA S.P.A. (IT) 2010-05-11 US disclosed
US-20090270535-A1 MIXTURES OF STERICALLY HINDERED AMINES FOR THE STABILISATION OF POLYMERS 3V SIGMA S.P.A. (IT) 2009-10-29 US disclosed
EP-2112198-A1 Mixtures of sterically hindered amines for the stabilisation of polymers 3V SIGMA S.p.A (IT) 2009-10-28 EP disclosed
US-20030153654-A1 Macromolecular hals with a definite molecular weight 3V SIGMA S.P.A. 2003-08-14 US disclosed
EP-1319643-A2 Macromolecular HALS with a definite molecular weight 3V SIGMA S.p.A (IT) 2003-06-18 EP disclosed