Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4407463 | 0.82 | TDP1 (0.40) | TDP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7751798 | 0.81 | MAPT (0.49) | TDP1CA12CA1CA2CA7 | |
| SCHEMBL498353 | 0.79 | LOXL2 (0.46) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL27487116 | 0.77 | CFTR (0.41) | CFTRTDP1CA12CA1CA2 | |
| SCHEMBL2111265 | 0.75 | TSHR (0.44) | CFTRCA1CA2CA9KDM4E | |
| SCHEMBL23645185 | 0.73 | CFTR (0.51) | CFTRTDP1CA12CA1CA2 | |
| SCHEMBL3238671 | 0.72 | CA1 (0.53) | TDP1CA12CA1CA2CA7 | |
| SCHEMBL2574864 | 0.72 | ESR1 (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL22263091 | 0.72 | CFTR (0.73) | CFTRCA12CA1CA2CA7 | |
| SCHEMBL4689121 | 0.71 | MEN1 (0.46) | CA1CA2ALDH1A1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700657-B2 | Vitamin D analogs | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-04-20 | — | — | US | disclosed |
| US-20040224929-A1 | Novel vitamin D analogs | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-11-11 | — | — | US | disclosed |