Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44179 | 0.98 | TSHR (0.64) | TSHRLMNAALDH1A1RECQLKMT2A | |
| SCHEMBL43894 | 0.95 | TSHR (0.61) | TSHRLMNAALDH1A1RECQLKMT2A | |
| SCHEMBL44285 | 0.95 | TSHR (0.61) | TSHRLMNAALDH1A1RECQLKMT2A | |
| Hydrochloric Acid SCHEMBL1266800 | 0.95 | TSHR (0.61) | TSHRLMNAALDH1A1RECQLKMT2A | |
| Hydrochloric Acid SCHEMBL120844 | 0.95 | TSHR (0.61) | TSHRLMNAALDH1A1RECQLKMT2A | |
| Hydrochloric Acid SCHEMBL164305 | 0.93 | TSHR (0.58) | TSHRLMNAALDH1A1RECQLKMT2A | |
| Hydrochloric Acid SCHEMBL351072 | 0.93 | TSHR (0.58) | TSHRLMNAALDH1A1RECQLKMT2A | |
| Hydrochloric Acid SCHEMBL3613959 | 0.93 | TSHR (0.58) | TSHRLMNAALDH1A1RECQLKMT2A | |
| Hydrochloric Acid SCHEMBL988663 | 0.93 | TSHR (0.58) | TSHRLMNAALDH1A1RECQLKMT2A | |
| SCHEMBL21563064 | 0.83 | TSHR (0.68) | TSHRLMNAALDH1A1RECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8927222-B2 | Method for the isolation of proteins binding to any kind nucleic acid sequence of interest | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2015-01-06 | — | — | US | claimed |
| US-20130196326-A1 | METHOD FOR THE ISOLATION OF PROTEINS BINDING TO ANY KIND NUCLEIC ACID SEQUENCE OF INTEREST | CNRS (FR) | 2013-08-01 | — | — | US | claimed |
| EP-2407552-B1 | Method for the isolation of the proteins bound to any kind of interesting nucleic acid sequence | CENTRE NAT RECH SCIENT (FR) | 2012-11-14 | — | — | EP | claimed |
| WO-2012007117-A1 | METHOD FOR THE ISOLATION OF PROTEINS BINDING TO ANY KIND NUCLEIC ACID SEQUENCE OF INTEREST | CNRS (FR) | 2012-01-19 | — | — | WO | claimed |
| EP-2407552-A1 | New method for the isolation of the proteins bound to any kind of interesting nucleic acid sequence | CNRS (FR) | 2012-01-18 | — | — | EP | claimed |