SCHEMBL328741

SCHEMBL328741

N#Cc1[c]nccc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL621799 0.68 TSHR (0.38)
SCHEMBL11549534 0.67
SCHEMBL1200619 0.66 ESR2 (0.41)
SCHEMBL4909130 0.66
SCHEMBL2645505 0.63 SMN1; SMN2 (0.31)
SCHEMBL12471054 0.63
SCHEMBL3059992 0.62
SCHEMBL49656 0.62
SCHEMBL317518 0.62
SCHEMBL285841 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1940 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12036291-B2 Probes for imaging huntingtin protein CHDI FOUNDATION, INC. (US) 2024-07-16 US claimed
WO-2024119977-A1 ORGANIC COMPOUND AND ORGANIC LIGHT EMISSION DIODE DEVICE COMPRISING SAME 四川阿格瑞新材料有限公司 2024-06-13 WO claimed
CN-118005611-A Probes for imaging huntingtin CHDI基金会股份有限公司 2024-05-10 CN claimed
US-20240150326-A1 CARBOXAMIDE COMPOUNDS AND USES THEREOF INCYTE CORPORATION 2024-05-09 US claimed
CN-112292380-B N- (phenyl) -2- (phenyl) pyrimidine-4-carboxamide derivatives and related compounds as HPK1 inhibitors for the treatment of cancer 因赛特公司 2024-04-05 CN claimed
EP-3634975-B1 17-OXIMES OF 15.BETA.-[3-PROPANAMIDO]-SUBSTITUTED ESTRA-1,3,5(10)-TRIEN-17-ONES FOR USE IN INHIBITION OF 17.BETA.-HYDROXYSTEROID DEHYDROGENASES ORGANON R&D FINLAND LTD (FI) 2024-02-28 EP claimed
WO-2024038818-A1 FUSED-RING POLYAZAACENE COMPOUND, AND PHOTOELECTRIC CONVERSION ELEMENT OR ORGANIC ELECTRONIC ELEMENT CONTAINING SAME 東ソー株式会社 2024-02-22 WO claimed
US-20240034737-A1 Heterocyclic Derivatives as P2X7 Receptor Antagonists BREYE THERAPEUTICS APS (DK) 2024-02-01 US claimed
US-20240025884-A1 COMPOUNDS AS GCN2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF DONG-A ST CO., LTD. (KR) 2024-01-25 US claimed
WO-2024009215-A1 NOVEL COMPOUNDS AS GCN2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF DONG-A ST CO., LTD. (KR) 2024-01-11 WO claimed
US-4435003-A COLOR FORMERS IN PRESSURE AND/OR HEAT SENSITIVE RECORDING MATERIALS CIBA-GEIGY CORPORATION (US) 1984-03-06 US claimed
US-4434174-A Treating cardiovascular diseases with N-(3-phenoxy-2-hydroxypropyl)benzimidazole-1-alkanamines BERLEX LABORATORIES, INC. (US) 1984-02-28 US claimed
US-4428935-A BETA-LACTAMASE INHIBITORS PFIZER INC. (US) 1984-01-31 US claimed
US-4363808-A N-(3-Phenoxy-2-hydroxypropyl)benzimidazole-1-alkanamines BERLEX LABORATORIES, INC. (US) 1982-12-14 US claimed
EP-0007605-B1 A PROCESS FOR INVERTING THE CONFIGURATION IN OPTICALLY ACTIVE COMPOUNDS AND OPTICALLY ACTIVE INTERMEDIATE COMPOUNDS AND THEIR SALTS REQUIRED THEREFOR CIBA-GEIGY AG (CH) 1982-09-15 EP claimed
US-4294966-A SALT FORMATION CIBA-GEIGY CORPORATION (US) 1981-10-13 US claimed
EP-0034116-A2 N-(3-phenoxy-2-hydroxypropyl)benzimidazole-1-alkanamines BERLEX LABORATORIES, INC. (US) 1981-08-19 EP claimed
EP-0007605-A1 A process for inverting the configuration in optically active compounds and optically active intermediate compounds and their salts required therefor CIBA-GEIGY AG (CH) 1980-02-06 EP claimed
EP-0006615-A1 Process for preparing epihalohydrin enantiomers MERCK & CO. INC. (US) 1980-01-09 EP claimed
US-4129735-A MULTISTAGE FROM AN OXAMIC ACID ESTER AND PHOSPHORUS PENTACHLORIDE AMERICAN HOME PRODUCTS CORPORATION (US) 1978-12-12 US claimed