Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1424593 | 0.83 | DGAT1 (0.70) | DGAT1 | |
| SCHEMBL4213240 | 0.82 | DGAT1 (0.73) | DGAT1 | |
| SCHEMBL13325118 | 0.80 | DGAT1 (0.72) | DGAT1 | |
| SCHEMBL17907350 | 0.76 | DGAT1 (0.66) | DGAT1 | |
| SCHEMBL12208228 | 0.75 | DGAT1 (1.00) | DGAT1 | |
| SCHEMBL16532125 | 0.75 | DGAT1 (0.64) | DGAT1 | |
| SCHEMBL17918487 | 0.75 | DGAT1 (0.64) | DGAT1 | |
| SCHEMBL16532003 | 0.75 | DGAT1 (0.64) | DGAT1 | |
| SCHEMBL16532039 | 0.74 | DGAT1 (0.63) | DGAT1 | |
| SCHEMBL17907298 | 0.74 | DGAT1 (0.62) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718645-B2 | Substituted bicyclolactam compounds | PFIZER INC. (US) | 2010-05-18 | — | — | US | disclosed |
| US-20090137551-A1 | Substituted Bicyclolactam Compounds | PFIZER INC | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137551-A1 | Substituted Bicyclolactam Compounds | CHRM2, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CXCR2 | DGAT1 4238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.