SCHEMBL328790

SCHEMBL328790

C=C(C)C(=O)OC(C)Cn1c(=O)n(CCCO)c(=O)n(CC(C)OC(=O)C(=C)C)c1=O

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
PDE4A P27815 1/20 0.30
ADORA2A P29274 1/20 0.30
ADORA2B P29275 1/20 0.30
PDE4B Q07343 1/20 0.30
PDE4C Q08493 1/20 0.30
PDE4D Q08499 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL149716 0.88 TSHR (0.40) TSHR
SCHEMBL23810922 0.83 TSHR (0.39) TSHR
SCHEMBL3320292 0.82 TSHR (0.36) TSHR
SCHEMBL152422 0.81 TSHR (0.33) TSHRPDE4AADORA2AADORA2BPDE4B
SCHEMBL5610090 0.77 TSHR (0.47) TSHRPDE4AADORA2AADORA2BPDE4B
SCHEMBL3249618 0.77 TSHR (0.47) TSHRPDE4AADORA2AADORA2BPDE4B
SCHEMBL9079243 0.76 TSHR (0.34) TSHR
SCHEMBL11738114 0.76 TSHR (0.33) TSHR
SCHEMBL11738612 0.76 TSHR (0.33) TSHR
SCHEMBL9077737 0.75 TSHR (0.36) TSHRPDE4AADORA2AADORA2BPDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2407969-B1 OPTICAL DISC DAINIPPON INK & CHEMICALS (JP) 2013-11-06 EP disclosed
EP-2413317-B1 ULTRAVIOLET-CURABLE COMPOSITION FOR OPTICAL DISC AND OPTICAL DISC DAINIPPON INK & CHEMICALS (JP) 2013-04-24 EP disclosed
EP-2495725-A1 UV CURABLE COMPOSITION FOR OPTICAL DISCS AND OPTICAL DISC DIC Corporation (JP) 2012-09-05 EP disclosed
EP-2413317-A1 ULTRAVIOLET-CURABLE COMPOSITION FOR OPTICAL DISC AND OPTICAL DISC DIC Corporation (JP) 2012-02-01 EP disclosed
EP-2407969-A1 OPTICAL DISC DIC Corporation (JP) 2012-01-18 EP disclosed
EP-1350816-B1 ACTIVE ENERGY RAY CURABLE COMPOSITION FOR COATING OPTICAL DISK AND OPTICAL DISK MITSUBISHI RAYON CO (JP) 2010-06-02 EP disclosed
EP-2169677-A1 ULTRAVIOLET-CURABLE COMPOSITION FOR LIGHT-TRANSMITTING LAYER AND OPTICAL DISK DIC Corporation (JP) 2010-03-31 EP disclosed
US-7341771-B2 Active energy ray curable composition for coating optical disk and optical disk MITSUBISHI RAYON CO., LTD. (JP) 2008-03-11 US disclosed
US-7132460-B2 Active energy ray curable composition for coating optical disk and optical disk MITSUBISHI RAYON CO., LTD. (JP) 2006-11-07 US disclosed
US-20060167200-A1 Active energy ray curable composition for coating optical disk and optical disk MITSUBISHI RAYON CO., LIMITED (JP) 2006-07-27 US disclosed
US-20040013976-A1 Active energy ray curable composition for coating optical disk and optical disk MITSUBISHI CHEMICAL CORPORATION (JP) 2004-01-22 US disclosed
EP-1350816-A1 ACTIVE ENERGY RAY CURABLE COMPOSITION FOR COATING OPTICAL DISK AND OPTICAL DISK Mitsubishi Rayon Co., Ltd. (JP) 2003-10-08 EP disclosed
US-5494645-A UV-CURING OF A COATED COMPOSITION OF COLLOICAL SILICA, AN UNSATURATED SILANE, A POLYACRYLOYLOXY-CONTAINING COMPOUND, A HYDROXY- AND ACRYLOYLOXY-CONTAINING TRIAZINE AND AN ACYLPHOSPHINE-TYPE PHOTOINITIATOR MITSUBISHI RAYON CO., LTD. (JP) 1996-02-27 US disclosed
US-5449702-A Coating composition and process for producing abrasion-resistant synthetic resin molded articles MITSUBISHI RAYON CO., LTD. (JP) 1995-09-12 US disclosed