SCHEMBL149716

SCHEMBL149716

C=C(C)C(=O)OC(C)Cn1c(=O)n(CC(C)OC(=O)C(=C)C)c(=O)n(CC(C)OC(=O)C(=C)C)c1=O

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.40
ALDH1A1 P00352 2/20 0.34
THRB P10828 1/20 0.31
KMT2A Q03164 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3320292 0.94 TSHR (0.36) TSHRALDH1A1
SCHEMBL328790 0.88 TSHR (0.33) TSHR
SCHEMBL23810922 0.88 TSHR (0.39) TSHRALDH1A1THRB
SCHEMBL11738612 0.86 TSHR (0.33) TSHR
SCHEMBL11738114 0.86 TSHR (0.33) TSHR
SCHEMBL150975 0.79 SLC18A3 (0.35) TSHRALDH1A1THRB
SCHEMBL11528879 0.78 IDH1 (0.33) TSHRALDH1A1
SCHEMBL14370789 0.77 TSHR (0.47) TSHRALDH1A1THRB
SCHEMBL11772571 0.77 ALDH1A1 (0.49) TSHRALDH1A1
SCHEMBL24495842 0.76 SLC18A3 (0.33) TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4526920-A Contains poly(meth)acrylic ester of oxy or polyoxyalkane polyol, polymerization initiator, filler MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1985-07-02 US claimed
CN-110678448-A Triazine compound, curable composition, method for producing cured product, and cured product thereof 株式会社ADEKA 2020-01-10 CN disclosed
US-9982080-B2 Photocurable composition and hard coating agent ADEKA CORPORATION (JP) 2018-05-29 US disclosed
US-9753188-B2 Inorganic-organic hybrid material, optical material using the same, and inorganic-organic composite composition NIPPON KASEI CHEMICAL COMPANY LIMITED (JP) 2017-09-05 US disclosed
EP-2842971-B1 PHOTOCURABLE COMPOSITION AND HARD COAT AGENT ADEKA CORP (JP) 2017-01-18 EP disclosed
US-9316907-B2 Photosensitive resin composition and uses thereof CHI MEI CORPORATION (TW) 2016-04-19 US disclosed
EP-2586826-B1 INORGANIC-ORGANIC HYBRID MATERIAL, OPTICAL MATERIAL USING SAME, AND INORGANIC-ORGANIC COMPOSITE COMPOSITION NIPPON KASEI CHEM (JP) 2015-11-25 EP disclosed
EP-2842971-A1 PHOTOCURABLE COMPOSITION AND HARD COAT AGENT Adeka Corporation (JP) 2015-03-04 EP disclosed
US-20150005441-A1 PHOTOCURABLE COMPOSITION AND HARD COATING AGENT ADEKA CORPORATION (JP) 2015-01-01 US disclosed
US-20140316033-A1 INORGANIC-ORGANIC HYBRID MATERIAL, OPTICAL MATERIAL USING THE SAME, AND INORGANIC-ORGANIC COMPOSITE COMPOSITION NIPPON KASEI CHEMICAL COMPANY LIMITED (JP) 2014-10-23 US disclosed
US-6306502-B1 COMPOSITION COMPRISING ULTRAVIOLET-CURABLE SILICONE, MONOMER MIXTURE COMPRISING TRIS((METH)ACRYLOYLOXYALKYL)ISOCYANURATE AND URETHANE POLY(METH)ACRYLATE HAVING ALICYCLIC SKELETON, PHOTOPOLYMERIZATION INITIATOR MITSUBISHI RAYON CO., LTD. (JP) 2001-10-23 US disclosed
EP-0754736-B1 HARDENABLE COATING RESIN COMPOSITION, COATED MATERIALS AND CONTAINERS, AND PROCESS FOR PRODUCING THEM MITSUI CHEMICALS INC (JP) 2000-10-18 EP disclosed
EP-0899091-A2 Transparent coated molded product and method for producing the same Asahi Glass Company Ltd. (JP) 1999-03-03 EP disclosed
EP-0869154-A1 COATING COMPOSITION FORMING WEAR-RESISTANT COAT AND ARTICLE COVERED WITH THE COAT MITSUBISHI RAYON CO., LTD. (JP) 1998-10-07 EP disclosed
US-5789459-A ACRYLATED TRIAZINES REACTED WITH ACRYLATED POLYOLS, COATINGS FOR PLASTIC BOTTLES, IMPROVED DURABILITY ALLOWS REUSE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1998-08-04 US disclosed
US-5693390-A ACRYLIC COATING FOR RETURNABLE BOTTLE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-12-02 US disclosed
EP-0754736-A1 HARDENABLE COATING RESIN COMPOSITION, COATED MATERIALS AND CONTAINERS, AND PROCESS FOR PRODUCING THEM MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-01-22 EP disclosed
EP-0100688-B1 CURABLE COATING COMPOSITION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1987-04-22 EP disclosed
US-4526920-A Contains poly(meth)acrylic ester of oxy or polyoxyalkane polyol, polymerization initiator, filler MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1985-07-02 US disclosed
EP-0100688-A2 Curable coating composition MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1984-02-15 EP disclosed