SCHEMBL3288109

SCHEMBL3288109

CCCCOC(=O)CCc1cc(-n2nc3ccccc3n2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
KDM4E B2RXH2 1/20 0.42
ALOX5 P09917 1/20 0.40
GAA P10253 4/20 0.39
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.38
MAOB P27338 3/20 0.38
MAOA P21397 2/20 0.38
TDP1 Q9NUW8 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
ATM Q13315 1/20 0.37
CNR2 P34972 1/20 0.36
ACHE P22303 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5514206 0.97 ALDH1A1 (0.42) ALDH1A1KDM4EALOX5GAAKMT2A
SCHEMBL29768836 0.97 ALDH1A1 (0.41) ALDH1A1KDM4EALOX5GAAKMT2A
SCHEMBL906105 0.97 ALDH1A1 (0.41) ALDH1A1KDM4EALOX5GAAKMT2A
SCHEMBL9871733 0.96 CNR2 (0.41) ALDH1A1KDM4EALOX5GAAKMT2A
SCHEMBL2491248 0.96 CNR2 (0.41) ALDH1A1KDM4EALOX5GAAKMT2A
SCHEMBL23533531 0.96 CNR2 (0.41) ALDH1A1KDM4EALOX5GAAKMT2A
SCHEMBL5630244 0.96 CNR2 (0.41) ALDH1A1KDM4EALOX5GAAKMT2A
SCHEMBL30996211 0.96 ALDH1A1 (0.40) ALDH1A1KDM4EALOX5GAAKMT2A
SCHEMBL29397430 0.96 CNR2 (0.41) ALDH1A1KDM4EALOX5GAAKMT2A
SCHEMBL29145739 0.96 CNR2 (0.41) ALDH1A1KDM4EALOX5GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2267523-A2 Stabilized electrochromic media BASF SE (DE) 2010-12-29 EP claimed
US-7595011-B2 One or more solvents, one or more materials which are functional elements of electrochromic devices, one or more ultraviolet light absorbers selected from hydroxyphenylbenzotriazoles and tris-aryl-s-triazines, and one or more NH or N-alkyl hindered amine light stabilizers; discoloration inhibition CIBA SPECIALTY CHEMICALS CORPORATION (US) 2009-09-29 US claimed
CN-100520551-C Electrochromic medium composition, preparation method thereof and electroactive device comprising same CIBA SC HOLDING AG (CH) 2009-07-29 CN claimed
CN-1985214-A Stable electrochromic medium CIBA SC HOLDING AG (CH) 2007-06-20 CN claimed
US-20060007519-A1 Stabilized electrochromic media CIBA SPECIALTY CHEMICALS CORP. 2006-01-12 US claimed
EP-1896550-B1 STABILIZED ELECTROCHROMIC MEDIA BASF SE (DE) 2013-08-14 EP disclosed
EP-2267523-A2 Stabilized electrochromic media BASF SE (DE) 2010-12-29 EP disclosed
US-7718096-B2 Stabilized electrochromic media CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-05-18 US disclosed
US-7595011-B2 One or more solvents, one or more materials which are functional elements of electrochromic devices, one or more ultraviolet light absorbers selected from hydroxyphenylbenzotriazoles and tris-aryl-s-triazines, and one or more NH or N-alkyl hindered amine light stabilizers; discoloration inhibition CIBA SPECIALTY CHEMICALS CORPORATION (US) 2009-09-29 US disclosed
CN-100520551-C Electrochromic medium composition, preparation method thereof and electroactive device comprising same CIBA SC HOLDING AG (CH) 2009-07-29 CN disclosed
EP-1896550-A1 STABILIZED ELECTROCHROMIC MEDIA Ciba Specialty Chemicals Holding Inc. (CH) 2008-03-12 EP disclosed
CN-1985214-A Stable electrochromic medium CIBA SC HOLDING AG (CH) 2007-06-20 CN disclosed
EP-1789842-A1 STABILIZED ELECTROCHROMIC MEDIA CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) 2007-05-30 EP disclosed
WO-2007003508-A1 STABILIZED ELECTROCHROMIC MEDIA CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2007-01-11 WO disclosed
US-20070002423-A1 Stabilized electrochromic media CIBA SPECIALTY CHEMICALS CORP. 2007-01-04 US disclosed
WO-2006005691-A1 STABILIZED ELECTROCHROMIC MEDIA CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-01-19 WO disclosed
US-20060007519-A1 Stabilized electrochromic media CIBA SPECIALTY CHEMICALS CORP. 2006-01-12 US disclosed
US-5032498-A Soluble stabilizers CIBA-GEIGY CORPORATION (US) 1991-07-16 US disclosed
US-4973702-A AMIDES AND ESTERS, UV STABILIZERS FOR PLASTICS AND PHOTOGRAPHIC MATERIALS CIBA-GEIGY CORPORATION (US) 1990-11-27 US disclosed
US-4853471-A 2-(2-Hydroxyphenyl)-benztriazoles, their use as UV-absorbers and their preparation CIBA-GEIGY CORPORATION (US) 1989-08-01 US disclosed