Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Guaiacol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.60 |
| ▸ | CA2 | P00918 | 3/20 | 0.60 |
| ▸ | CA7 | P43166 | 2/20 | 0.60 |
| ▸ | CA9 | Q16790 | 2/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | CA4 | P22748 | 1/20 | 0.60 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.60 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.48 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.48 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guaiacol SCHEMBL9363005 | 0.95 | CA1 (0.60) | CA1CA2CA7CA9CA12 | |
| Guaiacol SCHEMBL9419753 | 0.95 | CA1 (0.60) | CA1CA2CA7CA9CA12 | |
| Guaiacol SCHEMBL678968 | 0.95 | CA1 (0.60) | CA1CA2CA7CA9CA12 | |
| Guaiacol SCHEMBL3289583 | 0.95 | CA1 (0.60) | CA1CA2CA7CA9CA12 | |
| Guaiacol SCHEMBL6063786 | 0.95 | CA1 (0.60) | CA1CA2CA7CA9CA12 | |
| Guaiacol SCHEMBL9192643 | 0.81 | CA1 (0.44) | CA1CA2CA7CA9CA12 | |
| Lithium Ion SCHEMBL1136822 | 0.78 | CA1 (0.46) | CA1CA2CA7CA9CA12 | |
| 1,2-Dimethoxybenzene SCHEMBL5308636 | 0.76 | CA1 (1.00) | CA1CA2CA7CA9CA12 | |
| 1,2-Dimethoxybenzene SCHEMBL29351917 | 0.76 | CA1 (1.00) | CA1CA2CA7CA9CA12 | |
| 1,2-Dimethoxybenzene SCHEMBL105872 | 0.76 | CA1 (1.00) | CA1CA2CA7CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025120994-A1 | SECONDARY BATTERY NON-AQUEOUS ELECTROLYTE AND SECONDARY BATTERY PROVIDED WITH SAME | ステラケミファ株式会社 | 2025-06-12 | — | — | WO | disclosed |
| US-9587060-B2 | Functionalized rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2017-03-07 | — | — | US | disclosed |
| US-7714089-B2 | Functionalized monomers and functionalized rubbery polymers made therewith | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2010-05-11 | — | — | US | disclosed |
| US-20090156769-A1 | FUNCTIONALIZED MONOMERS AND FUNCTIONALIZED RUBBERY POLYMERS MADE THEREWITH | THE GOODYEAR TIRE & RUBBER COMPANY | 2009-06-18 | — | — | US | disclosed |
| EP-1967531-A1 | Method of making alkoxy functionalized rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2008-09-10 | — | — | EP | disclosed |
| US-7335706-B1 | Method of making alkoxy functionalized rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2008-02-26 | — | — | US | disclosed |
| US-7291687-B1 | Catalyst system for synthesizing rubbery polymers having a high trans microstructure content | THE GOODYEAR TIRE AND RUBBER COMPANY (US) | 2007-11-06 | — | — | US | disclosed |
| EP-1792892-A2 | Functionalized rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2007-06-06 | — | — | EP | disclosed |
| US-20070123631-A1 | Functionalized rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY | 2007-05-31 | — | — | US | disclosed |
| US-7222650-B2 | Tire with a tread comprising a rubbery polymer of a functionalized monomer | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2007-05-29 | — | — | US | disclosed |
| US-4110421-A | Catalytic process for the preparation of phosphazene polymers | ARMSTRONG CORK COMPANY (US) | 1978-08-29 | — | — | US | disclosed |
| US-4108805-A | FIRE RETARDANT | ARMSTRONG CORK COMPANY (US) | 1978-08-22 | — | — | US | disclosed |
| US-4107108-A | FOAMED FIRE-RETARDANT | ARMSTRONG CORK COMPANY (US) | 1978-08-15 | — | — | US | disclosed |
| US-4076658-A | BLOWING AGENT | ARMSTRONG CORK COMPANY (US) | 1978-02-28 | — | — | US | disclosed |
| US-4073824-A | FIRE RETARDANT, NONSMOKING | ARMSTRONG CORK COMPANY (US) | 1978-02-14 | — | — | US | disclosed |
| US-4055545-A | SOLID CARBOXYLIC ACID | ARMSTRONG CORK COMPANY (US) | 1977-10-25 | — | — | US | disclosed |
| US-4055520-A | FIRE RETARDANT | ARMSTRONG CORK COMPANY (US) | 1977-10-25 | — | — | US | disclosed |
| US-4055523-A | FIRE RETARDANT | ARMSTRONG CORK COMPANY (US) | 1977-10-25 | — | — | US | disclosed |
| US-4053456-A | CROSSLINKING, SMOKELESS | ARMSTRONG CORK COMPANY (US) | 1977-10-11 | — | — | US | disclosed |
| US-4026838-A | INCORPORATING A SOLID CARBOXYLIC ACID | ARMSTRONG CORK COMPANY (US) | 1977-05-31 | — | — | US | disclosed |