SCHEMBL328847

SCHEMBL328847

Clc1ccccc1NCNc1ccccc1Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.52
IDO1 P14902 1/20 0.52
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
ADRA2B P18089 1/20 0.46
ADRA2C P18825 1/20 0.46
LMNA P02545 3/20 0.45
TSHR P16473 2/20 0.45
EBP Q15125 1/20 0.42
SIGMAR1 Q99720 1/20 0.42
EPHB3 P54753 1/20 0.42
ALDH1A1 P00352 2/20 0.42
CYP1A2 P05177 2/20 0.42
HPGD P15428 1/20 0.42
CYP2C19 P33261 1/20 0.42
KDM4E B2RXH2 1/20 0.42
CXCL8 P10145 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HTT P42858 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29415424 1.00 MAPT (0.52) MAPTIDO1MEN1KMT2AADRA2B
Ammonia Solution, Strong SCHEMBL8970822 0.97 MAPT (0.50) MAPTIDO1MEN1KMT2AADRA2B
Ethylene SCHEMBL1818626 0.95 MAPT (0.48) MAPTIDO1MEN1KMT2AADRA2B
Piperazine SCHEMBL11283075 0.87 ADRA2B (0.50) MAPTIDO1MEN1KMT2AADRA2B
SCHEMBL9421891 0.84 MAPT (0.52) MAPTIDO1MEN1KMT2AADRA2B
SCHEMBL1000493 0.80 MEN1 (0.53) MAPTMEN1KMT2ALMNATSHR
SCHEMBL29353825 0.80 MEN1 (0.53) MAPTMEN1KMT2ALMNATSHR
SCHEMBL13446854 0.80 MAPT (0.48) MAPTIDO1MEN1KMT2AADRA2B
SCHEMBL3168264 0.80 MAPT (0.48) MAPTIDO1MEN1KMT2AADRA2B
SCHEMBL12651876 0.80 IDO1 (0.48) MAPTIDO1MEN1KMT2AADRA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2332 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3985777-B1 SECONDARY BATTERY LG ENERGY SOLUTION LTD (KR) 2025-09-03 EP claimed
US-20250250460-A1 COATING KIT AND METHOD FOR REPAIR AND/OR RECONSTITUTION OF RUBBER AND/OR METAL WORN AREAS BERTECH PANAMA S.A. (PA) 2025-08-07 US claimed
CN-119998349-A Two-component polyurethane for polycarbonate bonding 阿科玛法国 2025-05-13 CN claimed
CN-119798608-A Flame-retardant isocyanate, intrinsic flame-retardant polyurea elastomer and preparation method and application thereof 海洋化工研究院有限公司 2025-04-11 CN claimed
CN-118755440-A Insulating adhesive, positive plate and secondary battery 深圳好电科技有限公司 2024-10-11 CN claimed
CN-118401593-A Polymer foam, associated method and use 伍德利有限公司 2024-07-26 CN claimed
CN-114560184-B Shape-changeable polyurethane composite material container 安徽天元创涂新材料科技有限公司 2024-01-26 CN claimed
CN-115433452-B High-hardness thermoplastic polyurethane elastomer and preparation method thereof 盛鼎高新材料有限公司 2023-10-31 CN claimed
WO-2023151161-A1 POLYURETHANE COMPOSITE MATERIAL CONTAINER HAVING CHANGEABLE SHAPE 安徽天元创涂新材料科技有限公司 2023-08-17 WO claimed
CN-115678413-B Bi-component polyurethane waterproof paint and preparation method thereof 徐州卧牛山新型防水材料有限公司 2023-08-04 CN claimed
US-4299932-A ADDITION-CONDENSATION COPOLYMER OF A HYDROLYSED ISOCYANATE-AMIDE-MODIFIED DIENE, POLYURETHANE, AND POLYUREA THE FIRESTONE TIRE & RUBBER COMPANY (US) 1981-11-10 US claimed
US-4284746-A Perfluoroalkyl-substituted amines as epoxy resin curing agents DAIKIN KOGYO CO., LTD. (JP) 1981-08-18 US claimed
US-4235979-A Amine terminated polymers and the formation of block copolymers THE FIRESTONE TIRE & RUBBER COMPANY (US) 1980-11-25 US claimed
US-4134883-A ROLLS FROM BUTYLENE GLYCOL AND PROPYLENE GLYCOL, AN ISOCYANATE AND CHAIN EXTENDER WESTINGHOUSE ELECTRIC CORP. (US) 1979-01-16 US claimed
US-4120913-A MIXING LIQUID EPOXY RESIN AND AROMATIC AMINE AND SOLID EPOXY RESIN POWDER WESTINGHOUSE ELECTRIC CORP. (US) 1978-10-17 US claimed
US-4085165-A ISOCYANATE PREPOLYMER, VINYL COMPOUND, POLYAMINE OR POLYETHER CURING AGENT BRIDGESTONE TIRE CO., LTD. (JA) 1978-04-18 US claimed
US-4071492-A Polyurethane-urea elastomers based on propylene oxide-tetrahydrofuran copolymers THE FIRESTONE TIRE & RUBBER COMPANY (US) 1978-01-31 US claimed
US-3963681-A POLYETHERURETHANE COPOLYMERS BRIDGESTONE TIRE COMPANY LIMITED (JA) 1976-06-15 US claimed
US-3943107-A Processable high temperature polymers prepared from amine terminated polymers and cyanamides of polyfunctional secondary amines CIBA-GEIGY CORPORATION (US) 1976-03-09 US claimed
US-3933675-A FOR POLYURETHANES ANDERSON DEVELOPMENT COMPANY (US) 1976-01-20 US claimed