SCHEMBL3289449

SCHEMBL3289449

CN1c2ccccc2C(C)(C)C12/C=C\C=C/c1cc([N+](=O)[O-])ccc1O2

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.60
GAA P10253 4/20 0.60
MEN1 O00255 4/20 0.60
KMT2A Q03164 4/20 0.60
NPSR1 Q6W5P4 4/20 0.60
LMNA P02545 4/20 0.60
RECQL P46063 3/20 0.60
TDP1 Q9NUW8 3/20 0.60
ALPG P10696 1/20 0.60
TP53 P04637 1/20 0.60
ALOX15 P16050 1/20 0.60
HSD17B10 Q99714 1/20 0.60
GFER P55789 1/20 0.59
SMN1; SMN2 Q16637 5/20 0.43
THRB P10828 5/20 0.43
PKM P14618 2/20 0.43
PLIN1 O60240 1/20 0.43
TSHR P16473 1/20 0.43
PLIN5 Q00G26 1/20 0.43
ABHD5 Q8WTS1 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3289455 1.00 MAPT (0.60) MAPTGAAMEN1KMT2ANPSR1
SCHEMBL29466131 0.92 MAPT (0.70) MAPTGAAMEN1KMT2ANPSR1
SCHEMBL79311 0.92 MAPT (0.70) MAPTGAAMEN1KMT2ANPSR1
SCHEMBL12922324 0.92 MAPT (0.70) MAPTGAAMEN1KMT2ANPSR1
SCHEMBL29492998 0.92 MAPT (0.70) MAPTGAAMEN1KMT2ANPSR1
Hydrochloric Acid SCHEMBL11789208 0.91 MAPT (0.69) MAPTGAAMEN1KMT2ANPSR1
SCHEMBL8680604 0.84 MAPT (0.60) MAPTGAAMEN1KMT2ANPSR1
SCHEMBL8680133 0.83 MEN1 (0.80) MAPTGAAMEN1KMT2ANPSR1
SCHEMBL8682012 0.82 MEN1 (0.56) MAPTGAAMEN1KMT2ANPSR1
SCHEMBL12193757 0.82 MAPT (0.58) MAPTGAAMEN1KMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7718325-B2 Photochromic material, inkless reimageable printing paper, and methods XEROX CORPORATION (US) 2010-05-18 US disclosed
US-7718325-B2 Photochromic material, inkless reimageable printing paper, and methods XEROX CORPORATION (US) 2010-05-18 US disclosed
US-7718325-B2 Photochromic material, inkless reimageable printing paper, and methods XEROX CORPORATION (US) 2010-05-18 US disclosed
US-20080311495-A1 PHOTOCHROMIC MATERIAL, INKLESS REIMAGEABLE PRINTING PAPER, AND METHODS XEROX CORPORATION (US) 2008-12-18 US disclosed
US-20080311495-A1 PHOTOCHROMIC MATERIAL, INKLESS REIMAGEABLE PRINTING PAPER, AND METHODS XEROX CORPORATION (US) 2008-12-18 US disclosed
US-20080311495-A1 PHOTOCHROMIC MATERIAL, INKLESS REIMAGEABLE PRINTING PAPER, AND METHODS XEROX CORPORATION (US) 2008-12-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080311495-A1 PHOTOCHROMIC MATERIAL, INKLESS REIMAGEABLE PRINTING PAPER, AND METHODS ILK, RB1, SMCHD1 MAPT 246/4885GAA 3865/4885MEN1 915/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.