Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 11/20 | 0.45 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GALK1 | P51570 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16294578 | 1.00 | PDK2 (0.45) | PDK2TDP2SMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL30132162 | 1.00 | PDK2 (0.45) | PDK2TDP2SMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL15183981 | 0.89 | PDK2 (0.38) | PDK2TDP2SMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL15183983 | 0.89 | PDK2 (0.38) | PDK2TDP2SMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL15183998 | 0.89 | PDK2 (0.38) | PDK2TDP2SMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL15183988 | 0.89 | PDK2 (0.38) | PDK2TDP2SMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL9781137 | 0.89 | APEX1 (0.43) | PDK2APEX1PGR | |
| SCHEMBL20989880 | 0.89 | PDK2 (0.37) | PDK2TDP2L3MBTL1MAPTAPEX1 | |
| SCHEMBL20051796 | 0.89 | PDK2 (0.37) | PDK2TDP2L3MBTL1MAPTAPEX1 | |
| SCHEMBL536401 | 0.87 | MMP2 (0.46) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8981305-B2 | Index of refraction matched nanoparticles and methods of use | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-03-17 | — | — | US | claimed |
| US-20130026371-A1 | INDEX OF REFRACTION MATCHED NANOPARTICLES AND METHODS OF USE | CLEMSON UNIVERSITY (US) | 2013-01-31 | — | — | US | claimed |
| US-6303936-B1 | Extraction-scintillation medium and method of use | CLEMSON UNIVERSITY | 2001-10-16 | — | — | US | claimed |
| US-5420959-A | Scintillating optical fiber | NANOPTICS INCORPORATED (US) | 1995-05-30 | — | — | US | claimed |
| EP-0606732-A1 | High efficiency, high resolution, real-time radiographic imaging system | NANOPTICS INCORPORATED (US) | 1994-07-20 | — | — | EP | claimed |
| US-5308986-A | High efficiency, high resolution, real-time radiographic imaging system | NANOPTICS INCORPORATED (US) | 1994-05-03 | — | — | US | claimed |
| US-8981305-B2 | Index of refraction matched nanoparticles and methods of use | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-03-17 | — | — | US | disclosed |
| US-20130026371-A1 | INDEX OF REFRACTION MATCHED NANOPARTICLES AND METHODS OF USE | CLEMSON UNIVERSITY (US) | 2013-01-31 | — | — | US | disclosed |
| US-7723114-B1 | Methods and systems for detection of radionuclides | CLEMSON UNIVERSITY (US) | 2010-05-25 | — | — | US | disclosed |
| US-6303936-B1 | Extraction-scintillation medium and method of use | CLEMSON UNIVERSITY | 2001-10-16 | — | — | US | disclosed |
| US-5606638-A | Organic scintillator systems and optical fibers containing polycyclic aromatic compounds | NANOPTICS INCORPORATED (US) | 1997-02-25 | — | — | US | disclosed |
| US-5420959-A | Scintillating optical fiber | NANOPTICS INCORPORATED (US) | 1995-05-30 | — | — | US | disclosed |
| EP-0606732-A1 | High efficiency, high resolution, real-time radiographic imaging system | NANOPTICS INCORPORATED (US) | 1994-07-20 | — | — | EP | disclosed |
| US-5308986-A | High efficiency, high resolution, real-time radiographic imaging system | NANOPTICS INCORPORATED (US) | 1994-05-03 | — | — | US | disclosed |