SCHEMBL328997

SCHEMBL328997

C=CCCC(O)CCC=C

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.35
ALDH1A1 P00352 3/20 0.33
USP2 O75604 2/20 0.33
CYP3A4 P08684 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL28109667 0.97 TSHR (0.33) TSHRALDH1A1USP2CYP3A4MAPT
SCHEMBL18671478 0.89
SCHEMBL5868292 0.89
SCHEMBL2474318 0.87
SCHEMBL15115418 0.87
SCHEMBL28611328 0.85
SCHEMBL44830 0.85
SCHEMBL5716954 0.85
SCHEMBL28544020 0.85
SCHEMBL21385213 0.84 CA1 (0.34) ALDH1A1USP2CYP3A4MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103288590-A Method for synthesizing 5-iodine-1,8-nonadiene by using ultrasonic method UNIV JINAN 2013-09-11 CN claimed
US-6579997-B1 Enhanced activity of metal complexes UAB RESEARCH FOUNDATION 2003-06-17 US claimed
EP-1212134-A4 METALLACROWN ETHER CATALYSTS FOR HYDROFORMYLATION UAB RESEARCH FOUNDATION (US) 2003-01-22 EP claimed
EP-1212134-A1 METALLACROWN ETHER CATALYSTS FOR HYDROFORMYLATION UAB Research Foundation (US) 2002-06-12 EP claimed
EP-1066236-A4 PROCESS FOR HYDROCARBONYLATIONS IN SUPERCRITICAL CARBON DIOXIDE RES FOUNDATION OF (US) 2001-06-06 EP claimed
WO-2001007156-A1 METALLACROWN ETHER CATALYSTS FOR HYDROFORMYLATION UAB RESEARCH FOUNDATION (US) 2001-02-01 WO claimed
EP-1066236-A1 PROCESS FOR HYDROCARBONYLATIONS IN SUPERCRITICAL CARBON DIOXIDE The Research Foundation of State University of New York (US) 2001-01-10 EP claimed
WO-1999050214-A1 PROCESS FOR HYDROCARBONYLATIONS IN SUPERCRITICAL CARBON DIOXIDE THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1999-10-07 WO claimed
US-5962744-A USING CATALYST COMPLEX CONTAINING TRANSITION METAL AND PHOSPHITE LIGAND THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1999-10-05 US claimed
US-20250346602-A1 LACTAM SUBSTITUTED IMIDAZOPYRIDAZINE IL-17A MODULATORS AND USES THEREOF DICE ALPHA INC (US) 2025-11-13 US disclosed
CN-120202184-A Ionizable lipids and lipid nanoparticle compositions for delivery of nucleic acids 海狼治疗公司 2025-06-24 CN disclosed
EP-4525987-A1 LACTAM SUBSTITUTED IMIDAZOPYRIDAZINE IL-17A MODULATORS AND USES THEREOF Dice Alpha, Inc. (US) 2025-03-26 EP disclosed
WO-2024107906-A2 IONIZABLE LIPIDS AND LIPID NANOPARTICLE COMPOSITIONS FOR THE DELIVERY OF NUCLEIC ACIDS SEAWOLF THERAPEUTICS, INC. (US) 2024-05-23 WO disclosed
WO-2023225664-A1 LACTAM SUBSTITUTED IMIDAZOPYRIDAZINE IL-17A MODULATORS AND USES THEREOF DICE ALPHA, INC. (US) 2023-11-23 WO disclosed
US-5336435-A High polymer and ferroelectric liquid crystal composition utilizing same IDEMITSU KOSAN CO., LTD. (JP) 1994-08-09 US disclosed
US-5281685-A Polyether pendant groups, polysiloxane repeating units IDEMITSU KOSAN CO., LTD. (JP) 1994-01-25 US disclosed
US-5264517-A A-C copoly IDEMITSU KOSAN CO., LTD. (JP) 1993-11-23 US disclosed
EP-0548808-A2 High polymer and ferroelectric liquid crystal composition utilizing same IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-06-30 EP disclosed
EP-0542305-A2 High polymer and ferroelectric liquid crystal composition utilizing same IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-05-19 EP disclosed
EP-0493601-A1 LIQUID-CRYSTAL COPOLYMER, PRODUCTION THEREOF, DIENE COMPOUND USED IN SAID PRODUCTION, AND PRODUCTION OF SAID COMPOUND IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-07-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250346602-A1 LACTAM SUBSTITUTED IMIDAZOPYRIDAZINE IL-17A MODULATORS AND USES THEREOF IL17A, IL15, IL18 TSHR 4436/4885ALDH1A1 392/4885USP2 3119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.