Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 4/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CAMK2A | Q9UQM7 | 3/20 | 0.47 |
| ▸ | FABP4 | P15090 | 1/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.46 |
| ▸ | CFD | P00746 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | F11 | P03951 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.46 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18050387 | 0.86 | CXCL8 (0.50) | CXCL8AKR1B1CHRM1L3MBTL1TDP1 | |
| SCHEMBL2381169 | 0.85 | CXCL8 (0.56) | CXCL8AKR1B1CHRM1L3MBTL1TDP1 | |
| SCHEMBL18050520 | 0.84 | CXCL8 (0.48) | CXCL8AKR1B1CHRM1L3MBTL1CAMK2A | |
| SCHEMBL11097326 | 0.83 | CXCL8 (0.79) | CXCL8AKR1B1CHRM1L3MBTL1TDP1 | |
| SCHEMBL11847525 | 0.83 | MAPT (0.58) | CXCL8AKR1B1CHRM1L3MBTL1TDP1 | |
| SCHEMBL31112176 | 0.83 | MAPT (0.58) | CXCL8AKR1B1CHRM1L3MBTL1TDP1 | |
| SCHEMBL18050594 | 0.82 | CXCL8 (0.47) | CXCL8AKR1B1CHRM1L3MBTL1TDP1 | |
| SCHEMBL31112414 | 0.82 | CXCL8 (0.53) | CXCL8AKR1B1CHRM1L3MBTL1TDP1 | |
| SCHEMBL27374417 | 0.82 | CXCL8 (0.53) | CXCL8AKR1B1CHRM1L3MBTL1TDP1 | |
| SCHEMBL11217443 | 0.81 | CXCL8 (0.60) | CXCL8AKR1B1CHRM1L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7727434-B2 | Membranes and methods of treating membranes | GENERAL ELECTRIC COMPANY (US) | 2010-06-01 | — | — | US | disclosed |
| US-20070039874-A1 | Membranes and methods of treating membranes | GENERAL ELECTRIC COMPANY | 2007-02-22 | — | — | US | disclosed |