Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 6/20 | 0.35 |
| ▸ | CA2 | P00918 | 6/20 | 0.35 |
| ▸ | CA12 | O43570 | 4/20 | 0.35 |
| ▸ | CA9 | Q16790 | 4/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3288396 | 0.91 | TDP1 (0.53) | TDP1CA14MAOAMAOBMEN1 | |
| SCHEMBL6889562 | 0.88 | TDP1 (0.39) | TDP1CA14MAOAMAOBMEN1 | |
| SCHEMBL3293190 | 0.86 | CA14 (0.36) | TDP1CA14MAOAMAOBMEN1 | |
| SCHEMBL3287433 | 0.86 | CA14 (0.38) | TDP1CA14MAOAMAOBMEN1 | |
| SCHEMBL13327085 | 0.85 | TDP1 (0.46) | TDP1CA14MAOAMAOBMEN1 | |
| SCHEMBL3290841 | 0.84 | CA14 (0.36) | TDP1CA14MAOAMAOBMEN1 | |
| SCHEMBL16349523 | 0.82 | CA14 (0.50) | TDP1CA14MAOAMAOBMEN1 | |
| SCHEMBL7270004 | 0.81 | CA14 (0.58) | TDP1CA14MAOAMAOBMEN1 | |
| SCHEMBL7264039 | 0.81 | CA14 (0.58) | TDP1CA14MAOAMAOBMEN1 | |
| SCHEMBL19340291 | 0.80 | CA14 (0.57) | TDP1CA14MAOAMAOBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718157-B1 | Targeted lipid particles | BAKER TERENCE SEWARD | 2010-05-18 | — | — | US | disclosed |
| US-7531676-B2 | Lipids | CELLTECH R & D LIMITED (GB) | 2009-05-12 | — | — | US | disclosed |
| US-6583301-B1 | Bipolar; form complexes with polyanions; delivering bioactive substances such as nucleic acids to cells in vitro and in vivo | CELLTECH R & D LIMITED (GB) | 2003-06-24 | — | — | US | disclosed |