Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Glyphosate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 known ✓ | P03956 | 1/20 | 0.32 |
| ▸ | MMP8 known ✓ | P22894 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | GGH | Q92820 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glyphosate SCHEMBL20913742 | 0.98 | MEN1 (0.36) | MEN1LMNAHPGDTSHRBLM | |
| Glyphosate SCHEMBL27974141 | 0.91 | MEN1 (0.37) | MEN1LMNAHPGDTSHRBLM | |
| Glyphosate SCHEMBL30016870 | 0.91 | FFAR3 (0.43) | MEN1LMNAHPGDTSHRBLM | |
| Glyphosate SCHEMBL30579951 | 0.91 | LMNA (0.43) | MEN1LMNAHPGDTSHRBLM | |
| Glyphosate SCHEMBL1964442 | 0.91 | LMNA (0.43) | MEN1LMNAHPGDTSHRBLM | |
| Glyphosate SCHEMBL16440 | 0.91 | LMNA (0.43) | MEN1LMNAHPGDTSHRBLM | |
| Glyphosate SCHEMBL30579950 | 0.91 | LMNA (0.43) | MEN1LMNAHPGDTSHRBLM | |
| Glyphosate SCHEMBL214438 | 0.91 | LMNA (0.43) | MEN1LMNAHPGDTSHRBLM | |
| Glyphosate SCHEMBL29694166 | 0.91 | LMNA (0.43) | MEN1LMNAHPGDTSHRBLM | |
| Glyphosate SCHEMBL8515704 | 0.91 | LMNA (0.43) | MEN1LMNAHPGDTSHRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723265-B2 | Pesticide compositions containing oxalic acid | MONSANTO TECHNOLOGY (US) | 2010-05-25 | — | — | US | disclosed |
| US-6992045-B2 | Pesticide compositions containing oxalic acid | MONSANTO TECHNOLOGY LLC (US) | 2006-01-31 | — | — | US | disclosed |
| US-20060019830-A1 | Pesticide compositions containing oxalic acid | MONSANTO TECHNOLOGY LLC (US) | 2006-01-26 | — | — | US | disclosed |
| EP-1389912-A2 | PESTICIDE COMPOSITIONS CONTAINING OXALIC ACID | Monsanto Technology LLC (US) | 2004-02-25 | — | — | EP | disclosed |
| WO-2002069718-A2 | PESTICIDE COMPOSITIONS CONTAINING OXALIC ACID | MONSANTO TECHNOLOGY LLC (US) | 2002-09-12 | — | — | WO | disclosed |
| US-20020123430-A1 | Pesticide compositions containing oxalic acid | MONSANTO TECHNOLOGY LLC | 2002-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060019830-A1 | Pesticide compositions containing oxalic acid | OTC, SLC47A1, SLC47A2 | MMP1 8/4885MMP8 174/4885MEN1 3332/4885 |
| US-20020123430-A1 | Pesticide compositions containing oxalic acid | OTC, SLC47A1, SLC47A2 | MMP1 8/4885MMP8 174/4885MEN1 3332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.