Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | CASP7 | P55210 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | RGS12 | O14924 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.57 |
| ▸ | MTOR | P42345 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4255330 | 0.89 | PARP1 (0.45) | PARP1MAPTNPSR1MEN1USP2 | |
| SCHEMBL11331683 | 0.87 | KDR (0.44) | PARP1MAPTNPSR1MEN1USP2 | |
| SCHEMBL7285369 | 0.87 | CDK5 (0.50) | PARP1MAPTNPSR1MEN1USP2 | |
| SCHEMBL20586425 | 0.84 | ALDH1A1 (0.47) | MAPTKDM4EALDH1A1GAACA1 | |
| SCHEMBL27958308 | 0.83 | MEN1 (0.57) | PARP1MAPTNPSR1MEN1USP2 | |
| SCHEMBL13901466 | 0.80 | KMT2A (0.59) | MAPTMEN1USP2KMT2APOLB | |
| SCHEMBL16420006 | 0.80 | ALDH1A1 (0.50) | MAPTCASP1KDM4EALDH1A1GAA | |
| SCHEMBL28460070 | 0.78 | GRM5 (0.54) | PARP1MAPTNPSR1MEN1USP2 | |
| SCHEMBL20631467 | 0.78 | MEN1 (0.51) | PARP1MAPTNPSR1MEN1USP2 | |
| SCHEMBL17045725 | 0.76 | PARP1 (0.58) | PARP1MAPTNPSR1MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1902180-B | Use of 4-cyano-naphthalene-1, 8-dicarboximide derivatives and related compounds for protecting organic materials from the damaging effects of light | BASF AG | 2010-08-25 | — | — | CN | disclosed |
| US-7714044-B2 | Use of 4-cyano-naphthalene-1, 8-dicarboximide derivatives and related compounds to protect organic material from the damaging effects of light | BASF AKITENGESELLSCHAFT (DE) | 2010-05-11 | — | — | US | disclosed |
| US-20070100033-A1 | Use of 4-cyano-naphthalene-1, 8-dicarboximide derivatives and related compounds to protect organic material from the damaging effects of light | BAST AKTIENGESELLSCHAFT (DE) | 2007-05-03 | — | — | US | disclosed |
| CN-1902180-A | Use of 4-cyano-naphthalene-1, 8-dicarboximide derivatives and related compounds for protecting organic materials from the damaging effects of light | BASF AG (DE) | 2007-01-24 | — | — | CN | disclosed |