SCHEMBL329253

SCHEMBL329253

CC(=O)Oc1ccc2c(c1)Oc1cc(OC(C)=O)ccc1C21OC(=O)c2cc(CCl)ccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSTP1 P09211 1/20 1.00
MAPT P10636 3/20 0.72
MEN1 O00255 3/20 0.72
KMT2A Q03164 3/20 0.72
HTT P42858 2/20 0.72
ALDH1A1 P00352 2/20 0.72
USP2 O75604 2/20 0.72
LMNA P02545 1/20 0.72
CYP3A4 P08684 1/20 0.52
FTO Q9C0B1 9/20 0.47
RECQL P46063 2/20 0.44
HPGD P15428 1/20 0.44
CYP2C19 P33261 1/20 0.44
BLM P54132 1/20 0.44
SMAD3 P84022 1/20 0.44
PRMT1 Q99873 1/20 0.44
ACE2 Q9BYF1 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
KCNH2 Q12809 1/20 0.41
ITPR3 Q14573 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29355604 1.00 GSTP1 (1.00) GSTP1MAPTMEN1KMT2AHTT
SCHEMBL4204743 0.84 GSTP1 (0.73) GSTP1MAPTMEN1KMT2AHTT
SCHEMBL20353147 0.84 MAPT (0.78) GSTP1MAPTMEN1KMT2AHTT
Fluorescein Diacetate SCHEMBL29453229 0.84 MAPT (1.00) GSTP1MAPTMEN1KMT2AHTT
Fluorescein Diacetate SCHEMBL29353816 0.84 MAPT (1.00) GSTP1MAPTMEN1KMT2AHTT
Fluorescein Diacetate SCHEMBL1028369 0.84 MAPT (1.00) GSTP1MAPTMEN1KMT2AHTT
Fluorescein Diacetate SCHEMBL31658971 0.84 MAPT (1.00) GSTP1MAPTMEN1KMT2AHTT
SCHEMBL29403728 0.83 MEN1 (0.77) GSTP1MAPTMEN1KMT2AHTT
SCHEMBL18677730 0.83 MAPT (0.77) GSTP1MAPTMEN1KMT2AHTT
SCHEMBL12639984 0.83 MEN1 (0.77) GSTP1MAPTMEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 869 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018203315-A1 METHOD FOR MICROORGANISM EXTRACTION AND/OR FOR DETERMINATION OF A MICROORGANISM MAIN RESISTANCE MECHANISM AND/OR THE MINIMUM INHIBITORY CONCENTRATION OF A THERAPEUTICAL AGENT, KITS AND USES THEREOF UNIVERSIDADE DO PORTO (PT) 2018-11-08 WO claimed
EP-2820147-B1 RAPID ANTIBIOTIC SUSCEPTIBILITY TESTING HARVARD COLLEGE (US) 2018-08-08 EP claimed
US-20180000704-A1 USES OF CO-CRYSTALS UNIV STRATHCLYDE (GB) 2018-01-04 US claimed
EP-3250643-A1 USES OF CO-CRYSTALS University of Strathclyde (GB) 2017-12-06 EP claimed
US-9632085-B2 Rapid antibiotic susceptibility testing PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2017-04-25 US claimed
WO-2016120642-A1 USES OF CO-CRYSTALS UNIVERSITY OF STRATHCLYDE (GB) 2016-08-04 WO claimed
EP-2507252-B1 HEAT-SENSITIVE SPIN-TRANSITION MATERIALS DOPED WITH ONE OR MORE FLUORESCENT AGENTS CENTRE NAT RECH SCIENT (FR) 2016-02-17 EP claimed
US-20150064703-A1 RAPID ANTIBIOTIC SUSCEPTIBILITY TESTING PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2015-03-05 US claimed
EP-2820147-A1 RAPID ANTIBIOTIC SUSCEPTIBILITY TESTING President and Fellows of Harvard College (US) 2015-01-07 EP claimed
WO-2013130875-A1 RAPID ANTIBIOTIC SUSCEPTIBILITY TESTING PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2013-09-06 WO claimed
EP-2619575-A1 METHOD FOR THE DETECTION AND/OR QUANTIFICATION OF THE INTERACTION OF PLATELETS WITH INTERACTION PARTNERS SANOFI (FR) 2013-07-31 EP claimed
US-20130189714-A1 METHOD FOR THE DETECTION AND/OR QUANTIFICATION OF THE INTERACTION OF PLATELETS WITH INTERACTION PARTNERS SANOFI (FR) 2013-07-25 US claimed
WO-2012038370-A1 METHOD FOR THE DETECTION AND/OR QUANTIFICATION OF THE INTERACTION OF PLATELETS WITH INTERACTION PARTNERS SANOFI (FR) 2012-03-29 WO claimed
EP-2431739-A1 Method for the detection and/or quantification of the interaction of platelets with interaction partners SANOFI (FR) 2012-03-21 EP claimed
US-7892724-B2 Method for enhancing the viability of mammalian cells, tissues and organs using a solution comprising two low molecular weight PEGs WARSAW ORTHOPEDIC, INC 2011-02-22 US claimed
US-20090017439-A1 COMPOSITIONS AND METHODS FOR ENHANCING THE VIABILITY OF ANIMAL CELLS, TISSUES, AND ORGAN EXPLANTS WARSAW ORTHOPEDIC, INC. (US) 2009-01-15 US claimed
EP-0731664-B1 SENSOR WITH IMPROVED DRIFT STABILITY TERUMO CARDIOVASCULAR SYS (US) 2002-02-27 EP claimed
EP-0731664-A1 SENSOR WITH IMPROVED DRIFT STABILITY MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-09-18 EP claimed
WO-1995015114-A1 SENSOR WITH IMPROVED DRIFT STABILITY MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-06-08 WO claimed
US-5403746-A Aqueous first phase comprising pH sensitive indicator in buffer solution dispersed in hydrophobic second phase permeable to analyte and impermeable to ionized hydrogen MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-04-04 US claimed