Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28027092 | 1.00 | TSHR (0.46) | TSHRADRA1APDE4DHCAR2GAA | |
| SCHEMBL29220140 | 0.85 | TSHR (0.48) | TSHRADRA1APDE4DHCAR2GAA | |
| SCHEMBL27948179 | 0.83 | TSHR (0.48) | TSHRADRA1APDE4DHCAR2GAA | |
| SCHEMBL29220282 | 0.82 | TSHR (0.58) | TSHRADRA1APDE4DHCAR2GAA | |
| SCHEMBL23466330 | 0.78 | TSHR (0.48) | TSHRADRA1APDE4DHCAR2GAA | |
| SCHEMBL12020274 | 0.78 | TSHR (0.42) | TSHRADRA1APDE4DHCAR2GAA | |
| SCHEMBL16708428 | 0.77 | TSHR (0.52) | TSHRADRA1APDE4DHCAR2GAA | |
| SCHEMBL27844558 | 0.76 | TSHR (0.40) | TSHRADRA1APDE4DHCAR2GAA | |
| SCHEMBL10575347 | 0.76 | TSHR (0.46) | TSHRADRA1APDE4DHCAR2GAA | |
| SCHEMBL3293160 | 0.76 | TSHR (0.40) | TSHRADRA1APDE4DHCAR2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7736634-B2 | Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof | SIGMA COATINGS B.V. (NL) | 2010-06-15 | — | — | US | claimed |