Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29220140 | 0.90 | TSHR (0.48) | TSHRADRA1APDE4DSMN1; SMN2GAA | |
| SCHEMBL10011724 | 0.87 | ALDH1A1 (0.41) | TSHRSMN1; SMN2ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL10011723 | 0.87 | ALDH1A1 (0.41) | TSHRSMN1; SMN2ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL27844558 | 0.81 | TSHR (0.40) | TSHRADRA1APDE4DSMN1; SMN2GAA | |
| SCHEMBL12265742 | 0.79 | TSHR (0.48) | TSHRADRA1APDE4DSMN1; SMN2GAA | |
| SCHEMBL12020274 | 0.78 | TSHR (0.42) | TSHRADRA1APDE4DSMN1; SMN2GAA | |
| SCHEMBL27948179 | 0.78 | TSHR (0.48) | TSHRADRA1APDE4DSMN1; SMN2GAA | |
| SCHEMBL28027092 | 0.76 | TSHR (0.46) | TSHRADRA1APDE4DSMN1; SMN2GAA | |
| SCHEMBL3293163 | 0.76 | TSHR (0.46) | TSHRADRA1APDE4DSMN1; SMN2GAA | |
| SCHEMBL28808867 | 0.75 | ALDH1A1 (0.42) | TSHRSMN1; SMN2GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7736634-B2 | Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof | SIGMA COATINGS B.V. (NL) | 2010-06-15 | — | — | US | claimed |