Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Demannose. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Demannose SCHEMBL27640995 | 1.00 | LMNA (0.44) | LMNAL3MBTL1TDP1TP53PDE4A | |
| Demannose SCHEMBL28134059 | 0.96 | LMNA (0.44) | LMNAL3MBTL1TDP1TP53PDE4A | |
| Demannose SCHEMBL870938 | 0.96 | LMNA (0.44) | LMNAL3MBTL1TDP1TP53PDE4A | |
| Demannose SCHEMBL28107748 | 0.96 | LMNA (0.44) | LMNAL3MBTL1TDP1TP53PDE4A | |
| Demannose SCHEMBL870939 | 0.96 | LMNA (0.44) | LMNAL3MBTL1TDP1TP53PDE4A | |
| Demannose SCHEMBL28415027 | 0.96 | LMNA (0.44) | LMNAL3MBTL1TDP1TP53PDE4A | |
| Demannose SCHEMBL29777539 | 0.96 | LMNA (0.44) | LMNAL3MBTL1TDP1TP53PDE4A | |
| Demannose SCHEMBL27745349 | 0.96 | LMNA (0.44) | LMNAL3MBTL1TDP1TP53PDE4A | |
| Demannose SCHEMBL21403375 | 0.96 | LMNA (0.44) | LMNAL3MBTL1TDP1TP53PDE4A | |
| Demannose SCHEMBL27616123 | 0.92 | LMNA (0.41) | LMNAL3MBTL1TDP1TP53PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117143947-A | Induced fermentation process for producing collagen tripeptide by escherichia coli fermentation | 北京诺尼瑞生物科技有限责任公司 | 2023-12-01 | — | — | CN | claimed |
| CN-219376340-U | Filter equipment is used in preparation of magnesium sulfate glucose injection | 武汉博志宇恒科技有限公司 | 2023-07-21 | — | — | CN | claimed |
| CN-114774496-B | Method for preparing GLP-1 analogue through high-density fermentation | 北京惠之衡生物科技有限公司 | 2022-10-04 | — | — | CN | claimed |
| CN-117143947-A | Induced fermentation process for producing collagen tripeptide by escherichia coli fermentation | 北京诺尼瑞生物科技有限责任公司 | 2023-12-01 | — | — | CN | disclosed |
| CN-219376340-U | Filter equipment is used in preparation of magnesium sulfate glucose injection | 武汉博志宇恒科技有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-219376340-U | Filter equipment is used in preparation of magnesium sulfate glucose injection | 武汉博志宇恒科技有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-219376340-U | Filter equipment is used in preparation of magnesium sulfate glucose injection | 武汉博志宇恒科技有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-114774496-B | Method for preparing GLP-1 analogue through high-density fermentation | 北京惠之衡生物科技有限公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-114774496-A | Method for preparing GLP-1 analogue through high-density fermentation | 北京惠之衡生物科技有限公司 | 2022-07-22 | — | — | CN | disclosed |
| US-7732587-B2 | Nucleic acids encoding truncated soluble tumor necrosis factor | AMGEN INC. (US) | 2010-06-08 | — | — | US | disclosed |
| US-7381545-B2 | Method for controlling metallophosphate precipitation in high cell density fermentations | AMGEN INC. (US) | 2008-06-03 | — | — | US | disclosed |
| US-7118884-B1 | Method for controlling metallophosphate precipitation in high cell density fermentations | AMGEN INC. (US) | 2006-10-10 | — | — | US | disclosed |
| US-6989147-B2 | Truncated soluble tumor necrosis factor type-I and type-II receptors | AMGEN INC. (US) | 2006-01-24 | — | — | US | disclosed |
| US-20050250696-A1 | Truncated soluble tumor necrosis factor type-I and type-II receptors | FISHER ERIC F | 2005-11-10 | — | — | US | disclosed |
| US-20030054439-A1 | Truncated soluble tumor necrosis factor type-I and type-II receptors | AMGEN INC. | 2003-03-20 | — | — | US | disclosed |
| EP-0755438-B1 | METHOD FOR CONTROLLING METALLOPHOSPHATE PRECIPITATION IN HIGH CELL DENSITY FERMENTATIONS | AMGEN INC (US) | 2001-02-14 | — | — | EP | disclosed |
| EP-0914431-A2 | TRUNCATED SOLUBLE TUMOR NECROSIS FACTOR TYPE-I AND TYPE-II RECEPTORS | AMGEN INC. (US) | 1999-05-12 | — | — | EP | disclosed |
| WO-1998001555-A2 | TRUNCATED SOLUBLE TUMOR NECROSIS FACTOR TYPE-I AND TYPE-II RECEPTORS | AMGEN INC. (US) | 1998-01-15 | — | — | WO | disclosed |
| EP-0755438-A1 | METHOD FOR CONTROLLING METALLOPHOSPHATE PRECIPITATION IN HIGH CELL DENSITY FERMENTATIONS | AMGEN INC. (US) | 1997-01-29 | — | — | EP | disclosed |
| WO-1995029986-A1 | METHOD FOR CONTROLLING METALLOPHOSPHATE PRECIPITATION IN HIGH CELL DENSITY FERMENTATIONS | AMGEN INC. (US) | 1995-11-09 | — | — | WO | disclosed |