SCHEMBL3293446

SCHEMBL3293446

C=CC(=O)OCCCO[Si](C)(C)C

nearest known ligand 0.63

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.63
ALDH1A1 P00352 5/20 0.63
CYP3A4 P08684 2/20 0.63
HPGD P15428 1/20 0.62
TP53 P04637 3/20 0.52
HIF1A Q16665 3/20 0.52
HSD17B10 Q99714 1/20 0.52
THRB P10828 3/20 0.43
MAPK1 P28482 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ATM Q13315 1/20 0.41
HCAR2 Q8TDS4 4/20 0.36
MAPT P10636 1/20 0.32
RAB9A P51151 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4596157 0.96 TSHR (0.69) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL11803424 0.94 TSHR (0.57) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL476966 0.88 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL8963456 0.85 TSHR (0.55) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL321925 0.85 TSHR (0.85) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL28010970 0.84 TSHR (0.58) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL8863682 0.83 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL5835079 0.83 TSHR (0.57) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL28470987 0.83 TSHR (0.81) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL11804010 0.82 TSHR (0.73) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11613602-B2 (Meth)acrylic block copolymer and active energy ray curable composition containing the same KURARAY CO., LTD. (JP) 2023-03-28 US claimed
CN-101604607-A Coating composition for interconnection part of electrode and comprise its plasma display SAMSUNG SDI CO LTD (KR) 2009-12-16 CN claimed
CN-101189271-A Functional materials and novel methods for the fabrication of microfluidic devices UNIV NORTH CAROLINA (US) 2008-05-28 CN claimed
EP-3712185-B1 (METH)ACRYLIC BLOCK COPOLYMER, AND ACTIVE-ENERGY-RAY-CURABLE COMPOSITION CONTAINING SAME KURARAY CO (JP) 2022-03-23 EP disclosed
EP-3712185-A1 (METH)ACRYLIC BLOCK COPOLYMER, AND ACTIVE-ENERGY-RAY-CURABLE COMPOSITION CONTAINING SAME Kuraray Co., Ltd. (JP) 2020-09-23 EP disclosed
EP-3327053-B1 (METH)ACRYLIC BLOCK COPOLYMER KURARAY CO (JP) 2020-03-25 EP disclosed
CN-110234226-A Antimicrobial non-thrombogenic polymer compositions 路博润先进材料公司 2019-09-13 CN disclosed
CN-109790243-A Three block prepolymer and its purposes in silicone hydrogels 庄臣及庄臣视力保护公司 2019-05-21 CN disclosed
US-20180208700-A1 (METH)ACRYLIC BLOCK COPOLYMER KURARAY CO., LTD. (JP) 2018-07-26 US disclosed
US-9988477-B2 (Meth) acrylic block copolymer and process for producing the same KURARAY CO., LTD. (JP) 2018-06-05 US disclosed
EP-3327053-A1 (METH)ACRYLIC BLOCK COPOLYMER Kuraray Co., Ltd. (JP) 2018-05-30 EP disclosed
EP-1137727-A1 AQUEOUS COATING COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-10-04 EP disclosed
US-6204319-B1 AB BLOCK COPOLYMER PIGMENT DISPERSANT RESIN OF AN A BLOCK OF A HYDROPHOBIC POLYMER HAVING AMINE GROUPS; AND A B BLOCK OF A HYDROPHILIC POLYMER HAVING HYDROXYL GROUPS AND CARBOXYL GROUPS E.I. DU PONT DE NEMOURS AND COMPANY 2001-03-20 US disclosed
US-6187854-B1 WEATHERPROOF COATINGS E. I. DU PONT DE NEMOURS AND COMPANY 2001-02-13 US disclosed
WO-2000026308-A1 AQUEOUS COATING COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-05-11 WO disclosed
EP-0996689-A1 PIGMENT DISPERSIONS CONTAINING HYDROXYLATED AB-BLOCK POLYMER DISPERSANT E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-05-03 EP disclosed
WO-1999003938-A1 PIGMENT DISPERSIONS CONTAINING HYDROXYLATED AB-BLOCK POLYMER DISPERSANT E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-01-28 WO disclosed
US-5859113-A COATINGS; POLYMER A SEGMENT CONSISTS OF POLYMERIZED GLYCIDYL (METH)ACRYLATE REACTED WITH AN ACID; POLYMER B SEGMENT CONTAINS REACTIVE HYDROXY ALKYL (METH)ACRYLATE MONOMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-01-12 US disclosed
US-5658988-A ONE-PACKAGE; AUTOMOBILE FINISHES KANSAI PAINT CO., LTD. (JP) 1997-08-19 US disclosed
US-3935342-A POLYMERIZATION WITH AN UNSATURATED SILYL MONOMER MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1976-01-27 US disclosed