SCHEMBL3294254

SCHEMBL3294254

N#Cc1cc(C#N)[nH]n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14347636 0.73
SCHEMBL538190 0.73
SCHEMBL15555797 0.73
SCHEMBL174542 0.73
SCHEMBL30986580 0.73
SCHEMBL12778740 0.73
SCHEMBL31466186 0.73
SCHEMBL31416750 0.69 ALOX15 (0.39)
SCHEMBL21597775 0.69
SCHEMBL21884190 0.69 KDM4E (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4711377-A1 STEROID COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF Shujing Biopharma Co., Ltd (CN) 2026-03-18 EP disclosed
CN-119344305-A 6% Ginkgolic acid microemulsion and application thereof 贵州大学 2025-01-24 CN disclosed
CN-119214153-A 3% Ginkgolic acid microemulsion and application thereof 贵州大学 2024-12-31 CN disclosed
CN-119214153-A 3% Ginkgolic acid microemulsion and application thereof 贵州大学 2024-12-31 CN disclosed
WO-2024230797-A1 STEROID COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF 上海枢境生物科技有限公司 2024-11-14 WO disclosed
US-12043623-B2 Purinones as ubiquitin-specific protease 1 inhibitors FORMA THERAPEUTICS, INC. (US) 2024-07-23 US disclosed
US-12043623-B2 Purinones as ubiquitin-specific protease 1 inhibitors FORMA THERAPEUTICS, INC. (US) 2024-07-23 US disclosed
US-11786575-B2 Endoparasitic depsipeptides ZOETIS SERVICES LLC (US) 2023-10-17 US disclosed
CN-111741956-B Antiparasitic depsipeptides 硕腾服务有限责任公司 2023-07-07 CN disclosed
US-11661437-B2 Steroid derivative regulators, method for preparing the same, and uses thereof JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) 2023-05-30 US disclosed
CN-103415519-B As 6,7-dihydro-pyrazol [1, the 5-a] pyrazine-4-yl amine derivatives that beta-secretase (BACE) inhibitor is useful JANSSEN PHARMACEUTICA N.V. (BE) 2016-03-02 CN disclosed
EP-2681219-B1 6,7-DIHYDRO-PYRAZOLO[1,5-A]PYRAZIN-4-YLAMINE DERIVATIVES USEFUL AS INHIBITORS OF BETA-SECRETASE (BACE) JANSSEN PHARMACEUTICA NV (BE) 2015-10-28 EP disclosed
EP-2681219-B1 6,7-DIHYDRO-PYRAZOLO[1,5-A]PYRAZIN-4-YLAMINE DERIVATIVES USEFUL AS INHIBITORS OF BETA-SECRETASE (BACE) JANSSEN PHARMACEUTICA NV (BE) 2015-10-28 EP disclosed
EP-2681219-A1 6,7-DIHYDRO-PYRAZOLO[1,5-A]PYRAZIN-4-YLAMINE DERIVATIVES USEFUL AS INHIBITORS OF BETA-SECRETASE (BACE) Janssen Pharmaceutica, N.V. (BE) 2014-01-08 EP disclosed
US-20140005200-A1 6,7-DIHYDRO-PYRAZOLO[1,5-a]PYRAZIN-4-YLAMINE DERIVATIVES USEFUL AS INHIBITORS OF BETA-SECRETASE (BACE) JANSSEN PHARMACEUTICA NV (BE) 2014-01-02 US disclosed
WO-2012117027-A1 6,7-DIHYDRO-PYRAZOLO[1,5-A]PYRAZIN-4-YLAMINE DERIVATIVES USEFUL AS INHIBITORS OF BETA-SECRETASE (BACE) JANSSEN PHARMACEUTICA NV (BE) 2012-09-07 WO disclosed
CN-101195672-B Method for producing olefin-copolymerization catalyst and method for producing olefin-copolymers SUMITOMO CHEMICAL CO 2011-07-06 CN disclosed
US-7732540-B2 Process for producing olefin copolymerization catalyst and process for producing olefin copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-08 US disclosed
US-20090018012-A1 Process for Producing Olefin Copolymerization Catalyst and Process for Producing Olefin Copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-15 US disclosed
CN-101195672-A Method for producing olefin-copolymerization catalyst and method for producing olefin-copolymers SUMITOMO CHEMICAL CO (JP) 2008-06-11 CN disclosed