Urethane

Urethane

SCHEMBL3295693

C=CC(=O)C=Cc1ccccc1.CCOC(N)=O

nearest known ligand 0.50

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
LMNA P02545 3/20 0.50
PLIN1 O60240 1/20 0.50
ALDH1A1 P00352 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C9 P11712 1/20 0.50
F3 P13726 1/20 0.50
RECQL P46063 1/20 0.50
PLIN5 Q00G26 1/20 0.50
ABHD5 Q8WTS1 1/20 0.50
RAB9A P51151 4/20 0.48
NPSR1 Q6W5P4 1/20 0.46
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
MAOA P21397 1/20 0.45
MAOB P27338 1/20 0.45
CTDSP1 Q9GZU7 1/20 0.45
NPC1 O15118 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urethane SCHEMBL7107500 0.99 MAPT (0.49) MAPTSMN1; SMN2LMNAPLIN1ALDH1A1
Urethane SCHEMBL5333079 0.99 MAPT (0.49) MAPTSMN1; SMN2LMNAPLIN1ALDH1A1
Urethane SCHEMBL1761138 0.97 MAPT (0.47) MAPTSMN1; SMN2LMNAPLIN1ALDH1A1
Cinnamic Acid SCHEMBL10893974 0.85 HDAC3 (0.61) MAPTSMN1; SMN2LMNAPLIN1ALDH1A1
Cinnamic Acid SCHEMBL10893981 0.85 HDAC3 (0.61) MAPTSMN1; SMN2LMNAPLIN1ALDH1A1
(Z)-1,2-Diphenylethene SCHEMBL28619147 0.85 CTDSP1 (0.58) MAPTSMN1; SMN2LMNAALDH1A1RAB9A
Styrene SCHEMBL1256040 0.82 MEN1 (0.53) MAPTSMN1; SMN2LMNAALDH1A1CYP1A2
SCHEMBL4421926 0.81 MAPT (0.75) MAPTSMN1; SMN2LMNAPLIN1ALDH1A1
SCHEMBL184544 0.81 MAPT (0.75) MAPTSMN1; SMN2LMNAPLIN1ALDH1A1
Styrene SCHEMBL7214028 0.81 MEN1 (0.49) MAPTSMN1; SMN2LMNAALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1834977-B1 OPTICAL REFRACTIVE INDEX-MODIFYING POLYMER COMPOSITION, HOLOGRAPHIC RECORDING MATERIAL AND METHOD OF CONTROLLING REFRACTIVE INDEX NITTO DENKO CORP (JP) 2013-08-21 EP disclosed
US-7727679-B2 Optical refractive index-modifying polymer composition, hologram recording material and method of controlling refractive index NITTO DENKO CORPORATION (JP) 2010-06-01 US disclosed
EP-1834977-A1 OPTICAL REFRACTIVE INDEX-MODIFYING POLYMER COMPOSITION, HOLOGRAM RECORDING MATERIAL AND METHOD OF CONTROLLING REFRACTIVE INDEX NITTO DENKO CORPORATION (JP) 2007-09-19 EP disclosed
US-20070128523-A1 Optical refractive index-modifying polymer composition, hologram recording material and method of controlling refractive index NITTO DENKO CORPORATION (JP) 2007-06-07 US disclosed