SCHEMBL4421926

SCHEMBL4421926

C=CC(=O)/C=C/c1ccccc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.75
F3 P13726 3/20 0.75
PLIN1 O60240 2/20 0.75
LMNA P02545 2/20 0.75
RECQL P46063 2/20 0.75
PLIN5 Q00G26 2/20 0.75
ABHD5 Q8WTS1 2/20 0.75
ALDH1A1 P00352 2/20 0.75
CYP2D6 P10635 2/20 0.75
CYP2C9 P11712 2/20 0.75
CYP1A2 P05177 1/20 0.75
SMN1; SMN2 Q16637 1/20 0.75
HDAC3 O15379 2/20 0.61
HDAC4 P56524 2/20 0.61
HDAC1 Q13547 2/20 0.61
HDAC2 Q92769 2/20 0.61
HDAC8 Q9BY41 2/20 0.61
HDAC6 Q9UBN7 2/20 0.61
TNKS O95271 1/20 0.61
HCAR2 Q8TDS4 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL184544 1.00 MAPT (0.75) MAPTF3PLIN1LMNARECQL
SCHEMBL22076970 0.96 MAPT (0.76) MAPTF3PLIN1LMNARECQL
Butadiene SCHEMBL5702353 0.96 MAPT (0.69) MAPTF3PLIN1LMNARECQL
Vinyl Chloride SCHEMBL7915756 0.94 MAPT (0.67) MAPTF3PLIN1LMNARECQL
Acrylonitrile SCHEMBL2549054 0.89 MAPT (0.60) MAPTF3PLIN1LMNARECQL
SCHEMBL20518814 0.86 MAPT (1.00) MAPTF3PLIN1LMNARECQL
SCHEMBL20846 0.86 MAPT (1.00) MAPTF3PLIN1LMNARECQL
SCHEMBL20856054 0.86 MAPT (1.00) MAPTF3PLIN1LMNARECQL
SCHEMBL22146 0.86 MAPT (1.00) MAPTF3PLIN1LMNARECQL
SCHEMBL28435740 0.86 MAPT (1.00) MAPTF3PLIN1LMNARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0676062-A1 PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS THE DOW CHEMICAL COMPANY (US) 1995-10-11 EP claimed
WO-1994015258-A1 PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS THE DOW CHEMICAL COMPANY (US) 1994-07-07 WO claimed
WO-2024129600-A1 GONADOTROPIN-RELEASING HORMONE RECEPTOR (GNRHR) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. (US) 2024-06-20 WO disclosed
WO-2022071987-A1 CYCLIC SULFONE ADDITIVES FOR LITHIUM ION BATTERIES NOHMs Technologies, Inc. (US) 2022-04-07 WO disclosed
US-10925286-B2 Synergistic chalcone containing composition of a nematicide TELLURIS BIOTECH INDIA PRIVATE LIMITED (IN) 2021-02-23 US disclosed
US-9299934-B2 Polymer for organic electroluminescent elements, and organic electroluminescent element using cured product of same NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2016-03-29 US disclosed
US-9299934-B2 Polymer for organic electroluminescent elements, and organic electroluminescent element using cured product of same NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2016-03-29 US disclosed
EP-2692751-A1 POLYMER FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING CURED PRODUCT OF SAME Nippon Steel & Sumikin Chemical Co., Ltd. (JP) 2014-02-05 EP disclosed
US-7598384-B2 Tetrahydroquinolinones and their use as antagonists of metabotropic glutamate receptors MERZ PHARMA GMBH & CO. KGAA (DE) 2009-10-06 US disclosed
EP-1723116-B1 TETRAHYDROQUINOLINONES AND THEIR USE AS ANTAGONISTS OF METABOTROPIC GLUTAMATE RECEPTORS MERZ PHARMA GMBH & CO KGAA (DE) 2008-09-24 EP disclosed
EP-1753512-B1 TETRAHYDROPYRIDOTHIOPHENES NYCOMED GMBH (DE) 2008-07-09 EP disclosed
EP-0282897-A3 ETHYNYL- AND ETHENYLSTYRYL KETONES F. HOFFMANN-LA ROCHE AG (CH) 1989-10-04 EP disclosed
EP-0318820-A2 Process for anodising surfaces of aluminium or aluminium alloys BASF Aktiengesellschaft (DE) 1989-06-07 EP disclosed
EP-0282897-A2 Ethynyl- and ethenylstyryl ketones F. HOFFMANN-LA ROCHE AG (CH) 1988-09-21 EP disclosed
EP-0023673-B1 DEVICE FOR PERFORMING A HEAT-SENSITIVE RECORDING, HEAT-SENSITIVE RECORDING SHEET, AND A METHOD FOR PERFORMING A HEAT-SENSITIVE RECORDING KABUSHIKI KAISHA TOSHIBA (JP) 1985-10-23 EP disclosed
US-4446467-A DIAZOTYPE PROCESS; PHOTOSENSITIVITY; PRINTING TICKET DAI NIPPON PRINTING CO., LTD. (JP) 1984-05-01 US disclosed
US-4421839-A DIAZOTYPE PROCESS DAI NIPPON PRINTING CO., LTD. (JP) 1983-12-20 US disclosed
US-4254244-A Light-sensitive materials VICKERS LIMITED (GB) 1981-03-03 US disclosed
EP-0023673-A2 Device for performing a heat-sensitive recording, heat-sensitive recording sheet, and a method for performing a heat-sensitive recording KABUSHIKI KAISHA TOSHIBA (JP) 1981-02-11 EP disclosed
US-4117039-A LIGHT SENSITIVE MATERIALS VICKERS LIMITED (GB) 1978-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10925286-B2 Synergistic chalcone containing composition of a nematicide CASP4, NOTCH4, IL4 MAPT 3265/4885F3 2223/4885PLIN1 1704/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.