SCHEMBL329640

SCHEMBL329640

Cc1ccccc1N1CCCCCCC1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB1 P08588 1/20 0.64
GAA P10253 2/20 0.62
ALDH1A1 P00352 5/20 0.57
HPGD P15428 2/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
KEAP1 Q14145 1/20 0.57
L3MBTL1 Q9Y468 4/20 0.56
MAPT P10636 4/20 0.56
NPSR1 Q6W5P4 1/20 0.56
MAPK1 P28482 2/20 0.55
ALDH1A3 P47895 2/20 0.55
TSHR P16473 2/20 0.54
POLB P06746 2/20 0.54
ALOX15 P16050 1/20 0.54
SLC18A3 Q16572 1/20 0.53
ATM Q13315 1/20 0.53
LMNA P02545 2/20 0.51
MCOLN3 Q8TDD5 1/20 0.51
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL329728 1.00 ADRB1 (0.64) ADRB1GAAALDH1A1HPGDSMN1; SMN2
SCHEMBL2332676 1.00 ADRB1 (0.64) ADRB1GAAALDH1A1HPGDSMN1; SMN2
SCHEMBL31468714 1.00 ADRB1 (0.64) ADRB1GAAALDH1A1HPGDSMN1; SMN2
SCHEMBL21065736 0.98 ADRB1 (0.62) ADRB1GAAALDH1A1HPGDSMN1; SMN2
Hydrochloric Acid SCHEMBL6767674 0.98 ADRB1 (0.62) ADRB1GAAALDH1A1HPGDSMN1; SMN2
SCHEMBL329301 0.98 ADRB1 (0.67) ADRB1GAAALDH1A1HPGDSMN1; SMN2
Hydrochloric Acid SCHEMBL16446848 0.95 ADRB1 (0.64) ADRB1GAAALDH1A1HPGDSMN1; SMN2
Bromide SCHEMBL7300370 0.95 ADRB1 (0.64) ADRB1GAAALDH1A1HPGDSMN1; SMN2
SCHEMBL21065768 0.95 ADRB1 (0.64) ADRB1GAAALDH1A1HPGDSMN1; SMN2
Lithium SCHEMBL31448665 0.95 ADRB1 (0.64) ADRB1GAAALDH1A1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2407507-B1 RUBBER COMPOSITION AND PNEUMATIC TIRE JSR CORP (JP) 2016-09-28 EP disclosed
US-9206264-B2 Method for producing modified conjugated diene based (co)polymer, modified conjugated diene based (co)polymer, and rubber composition JSR CORPORATION (JP) 2015-12-08 US disclosed
EP-1783143-B1 PROCESS FOR PRODUCING CONJUGATED DIENE COPOLYMER RUBBER JSR CORP (JP) 2014-10-15 EP disclosed
EP-1726598-B1 CONJUGATED-DIOLEFIN (CO)POLYMER RUBBER AND PROCESS FOR PRODUCING THE SAME JSR CORP (JP) 2014-05-07 EP disclosed
EP-2123687-B1 CONJUGATED DIOLEFIN COPOLYMER RUBBER, METHOD FOR PRODUCING THE SAME, RUBBER COMPOSITION AND TIRE JSR CORP (JP) 2013-08-21 EP disclosed
EP-2130842-B1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER, MODIFIED CONJUGATED DIENE POLYMER, AND RUBBER COMPOSITION JSR CORP (JP) 2013-05-15 EP disclosed
US-8178626-B2 Method for producing modified conjugated diene based (co)polymer, modified conjugated diene based (co)polymer, and rubber composition JSR CORPORATION (JP) 2012-05-15 US disclosed
US-20120108737-A1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE BASED (CO)POLYMER, MODIFIED CONJUGATED DIENE BASED (CO)POLYMER, AND RUBBER COMPOSITION JSR CORPORATION (JP) 2012-05-03 US disclosed
EP-2407507-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE JSR Corporation (JP) 2012-01-18 EP disclosed
US-20110319519-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE JSR CORPORATION (JP) 2011-12-29 US disclosed
EP-0992537-B1 Oil extended rubber and rubber composition JSR CORP (JP) 2004-12-29 EP disclosed
US-20040254301-A1 Conjugated diolefin (co)polymer rubber, process for producing (co)polymer rubber, rubber composition, composite, and tire JSR CORPORATION (JP) 2004-12-16 US disclosed
EP-1457501-A1 CONJUGATED DIOLEFIN POLYMER RUBBER PROCESS FOR PRODUCING POLYMER RUBBER RUBBER COMPOSITION COMPOSITE AND TIRE JSR Corporation (JP) 2004-09-15 EP disclosed
EP-0924227-B1 Conjugated diolefin-based copolymer rubber and composition thereof JSR CORP (JP) 2004-03-10 EP disclosed
US-20030125448-A1 A butadiene-styrene copolymer having end terminals modified with a tin compound and amino compound; molecular weight distribution, tire rolling resistance, hysteresis-free, wear resistance GOODYEAR TIRE & RUBBER COMPANY, THE 2003-07-03 US disclosed
EP-1318172-A1 Pneumatic tire having a rubber component containing a tin/amino functionalized rubber and an inversion carbon black THE GOODYEAR TIRE & RUBBER COMPANY (US) 2003-06-11 EP disclosed
US-6362272-B1 CONJUGATED DIOLEFIN AND AROMATIC VINYL COPOLYMER JSR CORPORATION (JP) 2002-03-26 US disclosed
US-6191234-B1 CONJUGATED DIENE-AROMATIC VINYL COPOLYMER OBTAINED BY MODIFYING POLYMER WITH A AMINO GROUP IS USED TO IMPROVE WET SKID RESISTANCE, WEAR RESISTANCE OF AUTOMOBILE TIRE TREAD JSR CORPORATION (JP) 2001-02-20 US disclosed
EP-0992537-A1 Oil extended rubber and rubber composition JSR Corporation (JP) 2000-04-12 EP disclosed
EP-0924227-A1 Conjugated diolefin-based copolymer rubber and composition thereof JSR Corporation (JP) 1999-06-23 EP disclosed