Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3294504 | 0.87 | L3MBTL1 (0.48) | GAAL3MBTL1NAMPTEPHX2MAPT | |
| SCHEMBL3296465 | 0.79 | L3MBTL1 (0.43) | GAAL3MBTL1NAMPTMAPTRECQL | |
| SCHEMBL3180689 | 0.78 | L3MBTL1 (0.61) | GAAL3MBTL1NAMPTMAPTRECQL | |
| SCHEMBL12270350 | 0.77 | GAA (0.53) | GAAL3MBTL1NAMPTMAPTRECQL | |
| SCHEMBL19734791 | 0.77 | L3MBTL1 (0.49) | GAAL3MBTL1NAMPTMAPTRECQL | |
| SCHEMBL5750637 | 0.77 | POLB (0.49) | POLBGAAL3MBTL1NAMPTMAPT | |
| SCHEMBL7166722 | 0.77 | POLB (0.82) | POLBGAAL3MBTL1NPSR1 | |
| SCHEMBL24455110 | 0.76 | L3MBTL1 (0.51) | GAAL3MBTL1NAMPTMAPTRECQL | |
| SCHEMBL3296454 | 0.76 | POLB (0.55) | POLBGAAL3MBTL1NPSR1 | |
| SCHEMBL14798817 | 0.76 | L3MBTL1 (0.47) | GAAL3MBTL1NAMPTMAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7736911-B2 | Activity-based probes for protein tyrosine phosphatases | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2010-06-15 | — | — | US | disclosed |
| WO-2005114197-A2 | ACTIVITY-BASED PROBES FOR PROTEIN TYROSINE PHOSPHATASES | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2005-12-01 | — | — | WO | disclosed |
| US-20050233469-A1 | Activity-based probes for protein tyrosine phosphatases | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY | 2005-10-20 | — | — | US | disclosed |