Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.30 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3773264 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL27520889 | 0.90 | TSHR (0.38) | TSHRLMNATHRBALDH1A1TDP1 | |
| SCHEMBL28619806 | 0.87 | TSHR (0.50) | TSHRLMNATHRBALDH1A1SLC22A1 | |
| SCHEMBL153637 | 0.85 | TSHR (0.46) | TSHRLMNATHRBALDH1A1TDP1 | |
| SCHEMBL9745743 | 0.82 | — | — | |
| Bromide SCHEMBL20500234 | 0.81 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL2140796 | 0.81 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| Iodide SCHEMBL20500143 | 0.81 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| Fluoride SCHEMBL27639896 | 0.81 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| SCHEMBL3767964 | 0.80 | TSHR (0.50) | TSHRLMNATHRBALDH1A1SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7736634-B2 | Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof | SIGMA COATINGS B.V. (NL) | 2010-06-15 | — | — | US | claimed |
| US-7595370-B2 | Reacting cyclosiloxane with unsaturated organosilylated carboxylate monomer or copolymer under presence of catalyst; antifouling paints, marine systems | PPG B.V. (NL) | 2009-09-29 | — | — | US | claimed |
| US-20060142516-A1 | Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof | SIGMA COATINGS B.V. (NL) | 2006-06-29 | — | — | US | claimed |
| EP-1539861-A1 | PROCESS FOR THE PREPARATION OF POLYORGANOSILYLATED CARBOXYLATE MONOMERS OR POLYMERS THEREOF | Sigmakalon Services B.V. (NL) | 2005-06-15 | — | — | EP | claimed |
| WO-2004007591-A1 | PROCESS FOR THE PREPARATION OF POLYORGANOSILYLATED CARBOXYLATE MONOMERS OR POLYMERS THEREOF | SIGMAKALON SERVICES B.V. (NL) | 2004-01-22 | — | — | WO | claimed |
| EP-1380611-A1 | Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof | SigmaKalon Group B.V. (NL) | 2004-01-14 | — | — | EP | claimed |
| WO-1999015537-A1 | TRANSITION METAL COMPOUND | TARGOR GMBH (DE) | 1999-04-01 | — | — | WO | claimed |
| CN-106747265-B | A kind of aerogel composite and its preparation method based on self assembly opacifier fiber | 广州大学 | 2019-04-02 | — | — | CN | disclosed |
| CN-106747265-A | A kind of aerogel composite and its preparation method based on self assembly opacifier fiber | 广州大学 | 2017-05-31 | — | — | CN | disclosed |
| EP-1795551-B1 | Polyorganosilylated carboxylate monomers and polymers and process for the preparation thereof | SIGMAKALON SERVICES B V (NL) | 2009-12-30 | — | — | EP | disclosed |
| US-7595370-B2 | Reacting cyclosiloxane with unsaturated organosilylated carboxylate monomer or copolymer under presence of catalyst; antifouling paints, marine systems | PPG B.V. (NL) | 2009-09-29 | — | — | US | disclosed |
| EP-1795551-A1 | Polyorganosilylated carboxylate monomers and polymers and process for the preparation thereof | Sigmakalon Services B.V. (NL) | 2007-06-13 | — | — | EP | disclosed |
| US-20060142516-A1 | Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof | SIGMA COATINGS B.V. (NL) | 2006-06-29 | — | — | US | disclosed |
| EP-1539861-A1 | PROCESS FOR THE PREPARATION OF POLYORGANOSILYLATED CARBOXYLATE MONOMERS OR POLYMERS THEREOF | Sigmakalon Services B.V. (NL) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004007591-A1 | PROCESS FOR THE PREPARATION OF POLYORGANOSILYLATED CARBOXYLATE MONOMERS OR POLYMERS THEREOF | SIGMAKALON SERVICES B.V. (NL) | 2004-01-22 | — | — | WO | disclosed |
| EP-1380611-A1 | Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof | SigmaKalon Group B.V. (NL) | 2004-01-14 | — | — | EP | disclosed |
| WO-1999015537-A1 | TRANSITION METAL COMPOUND | TARGOR GMBH (DE) | 1999-04-01 | — | — | WO | disclosed |
| US-4957989-A | ANTIFOULING AGENT FOR SHIP BOTTOMS, NONTOXIC | TOSHIBA SILICONE CO., LTD. (JP) | 1990-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142516-A1 | Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof | C1R, C9, PCBP1 | TSHR 3690/4885LMNA 3271/4885THRB 4122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.